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. 2020 Oct 26;70(1):92–105. doi: 10.1136/gutjnl-2020-322630

Table 2.

Test Baseline 6 months 12 months
Auto (n=10) Allo (n=10) P value Auto
(n=10)
Allo
(n=10)
P value Auto
(n=10)
Allo
(n=10)
P value
C peptide, fasting (pmol/L) 319±118 327±89 0.86 380±136 283±114 0.1 348±115 202±85 0.0045
C peptide, peak (t=90 min)(pmol/L) 766±264 748±369 0.9 855±350 671±371 0.27 805±255 511±342 0.043
C peptide, AUC (mmol/L/min) 77±21 78±33 0.92 89±35 69±36 0.24 85±27 53±33 0.032
Insulin dose (IU/kg/day) 0.49±0.13 0.43±0.24 0.55 0.41±0.10 0.37±0.18 0.57 0.47±0.10 0.45±0.18 0.71
HbA1c (mmol/mol) 78 (66–90) 78.5 (67–90) 0.68 45 (41–49) 48.5 (41–56) 0.41 46 (40–53) 53.5 (44–63) 0.19

The means±SD in the autologous and allogenic group at baseline, 6 and 12 months follow-up are shown. P values were calculated using the Student’s t-test. For HbA1c, the median and IQR (P25-P75) is shown, and the p value was calculated using a Mann-Whitney U test as it is not normally distributed. C peptide peak was measured at 90 min after ingestion of a mixed meal test. C peptide AUC designates the AUC of 120 min after the mixed meal with blood sampling at 0, 15, 30, 45, 60, 90 and 120 min.

AUC, area under the curve.