Table 2.
Flow measurements at baseline and following external ventilation in Fontan subjects and controls
| CMR flows (L/min/m2) |
Baseline | Post-NPV | P value | Post-BPV | P value |
| Fontan subjects (n=10) | |||||
| SVC | 0.72 (0.55–0.93) | 0.75 (0.59–0.90) | 0.652 | 0.80 (0.74–1.04) | 0.106 |
| Fontan | 1.75 (1.67–2.07) | 1.99 (1.88–2.47) | 0.049 | 2.36 (1.81–3.02) | 0.002 |
| Sub-IVC | 0.99 (0.80–1.37) | 1.16 (0.91–1.48) | 0.106 | 1.37 (0.88–1.80) | 0.027 |
| HV | 0.81 (0.62–1.03) | 0.96 (0.85–1.04) | 0.160 | 1.06 (0.84–1.42) | 0.049 |
| PoV | 0.51 (0.37–0.60) | 0.53 (0.45–0.75) | 0.129 | 0.55 (0.42–0.60) | 0.432 |
| PBF | 2.48 (2.33–2.99) | 2.88 (2.51–3.55) | 0.037 | 3.08 (2.70–3.76) | 0.002 |
| CO | 2.88 (2.28–3.35) | 2.82 (2.55–3.47) | 0.432 | 3.28 (2.81–3.72) | 0.010 |
| Controls (n=10) | |||||
| SVC | 1.05 (0.97–1.15) | 1.10 (0.92–1.17) | 0.770 | 1.01 (0.90–1.15) | 0.426 |
| Sup-IVC | 2.10 (1.97–2.38) | 2.06 (1.68–2.30) | 0.156 | 2.19 (1.77–2.47) | 0.557 |
| Sub-IVC | 1.33 (1.17–1.47) | 1.42 (1.18–1.60) | 0.770 | 1.39 (1.22–1.64) | 0.573 |
| HV | 0.79 (0.74–1.03) | 0.64 (0.57–0.96) | 0.065 | 0.87 (0.72–1.07) | 0.570 |
| PoV | 0.59 (0.51–0.78) | 0.63 (0.54–0.78) | 0.557 | 0.51 (0.48–0.64) | 0.275 |
| PBF | 3.37 (3.09–3.81) | 3.32 (2.86–3.68) | 0.232 | 2.97 (2.64–3.57) | 0.084 |
| CO | 2.97 (2.76–3.42) | 3.23 (2.78–3.43) | 0.846 | 3.13 (2.76–3.45) | 1.000 |
Data expressed as median (IQR).
Bolded figures are statistically significant to p<0.05
BPV, biphasic ventilation; CMR, cardiovascular magnetic resonance; CO, cardiac output; HV, hepatic vein; NPV, negative pressure ventilation; PBF, pulmonary blood flow; PoV, portal vein; Sub-IVC, subhepatic inferior vena cava; Sup-IVC, suprahepatic inferior vena cava; SVC, superior vena cava.