Table 1:
Demographic and medication information for 2406 participants
| Schizophrenia | Bipolar 1 disorder | Bipolar 2 disorder | Major depressive disorder | Controls | p value | |
|---|---|---|---|---|---|---|
| Sex | ||||||
| Female | 28/160 (17%) | 312/519 (60%) | 148/204 (72%) | 596/806 (74%) | 449/717 (63%) | ·· |
| Male | 132/160 (83%) | 207/519 (40%) | 56/204 (28%) | 210/806 (26%) | 268/717 (37%) | 0·47 |
| Age | 37·4 (12·8) | 44·1 (13·8) | 38·7 (14·4) | 39·3 (14·1) | 36·7 (14·45) | 2·71×10−9 |
| Education, years | 10·4 (3·3) | 11·1 (4·24) | 12·3 (3·7) | 11·9 (3·7) | 11·7 (3·5) | 0·370 |
| Premorbid IQ, WAT score | 27·13 (8·64) | 29·90 (10·03) | 31·85 (8·29) | 31·06 (8·12) | 29·93 (8·29) | 0·210 |
| Raw SA45 Global Severity Index | 38·6 (34·6) | 30·7 (31·0) | 55·2 (39·8) | 53 (37·9) | 12·5 (13·8) | NA |
| Number of hospital admissions and emergency room visits | 14·68 (16·34) | 12·21 (12·58) | 5·91 (9·00) | 3·71 (6·02) | NA | NA |
| Duration of illness, years | 8·2 (4·9) | 8·8 (4·6) | 5·9 (4·3) | 4·4 (3·8) | NA | NA |
| Antipsychotic use | 142/160 (89%) | 353/519 (68%) | 106/204 (52%) | 264/806 (33%) | 0/717 (0%) | NA |
| Antidepressant use | 43/160 (27%) | 119/519 (23%) | 95/204 (47%) | 577/806 (72%) | 1/717 (<1%) | NA |
| Mood stabiliser use | 37/160 (23%) | 363/519 (70%) | 138/204 (68%) | 151/806 (19%) | 5/717 (1%) | NA |
| In top half of psychosis factor score | 160/160 (100%) | 417/519 (80%) | 94/204 (46%) | 160/806 (20%) | NA | NA |
| In top half of mania factor score | 57/160 (36%) | 508/519 (98%) | 187/204 (92%) | 91/806 (11%) | NA | NA |
| In top half of depression factor score | 11/160 (7%) | 165/519 (32%) | 137/204 (67%) | 439/806 (54%) | NA | NA |
Data are n/N (%) or mean (SD). The p value compares all cases to controls. WAT=word accentuation test. NA=not applicable.