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. 2020 Oct 21;29(21):3504–3515. doi: 10.1093/hmg/ddaa234

Table 2.

Binucleated cardiomyocyte architectural parameters

Genotype Age (months) n (mice); n (cells) Length (μ) Width (μ) Area (μ2) Aspect ratio
+/+ 1 m 4; 160 108.0 ± 21.2 20.8 ± 4.7 1981.3 ± 535.6 5.2
−/− 4; 177 110.9 ± 19.8 19.9 ± 4.6 1963.5 ± 513.0 5.6
+/+ 4–6 m 6; 147 126.8 ± 28.0 24.8 ± 6.2 2802.3 ± 972.2 5.1
−/− 5; 119 107.6 ± 19.9 32.5 ± 7.0 2834.1 ± 721.9 3.3
I685T/I685T 4; 125 115.7 ± 24.2 28.9 ± 7.1 2846.2 ± 884.0 4.0
+/− 4; 170 131.3 ± 24.7 24.7 ± 5.7 2745.0 ± 824.7 5.3
K489R/− 4; 148 102.5 ± 22.4 33.5 ± 8.0 2827.0 ± 868.0 3.1
I685T/− 4; 142 112.8 ± 23.7 32.2 ± 8.4 2923.8 ± 961.7 3.5

Average (± standard deviation) cardiomyocyte lengths and widths and areas and calculated aspect ratios for the number of measured cells isolated from the number of mice indicated at the ages indicated. Statistical evaluations are shown in Figure 3A (4–6 months) and 3D (1 month).