Table 2.
Binucleated cardiomyocyte architectural parameters
Genotype | Age (months) | n (mice); n (cells) | Length (μ) | Width (μ) | Area (μ2) | Aspect ratio |
---|---|---|---|---|---|---|
+/+ | 1 m | 4; 160 | 108.0 ± 21.2 | 20.8 ± 4.7 | 1981.3 ± 535.6 | 5.2 |
−/− | 4; 177 | 110.9 ± 19.8 | 19.9 ± 4.6 | 1963.5 ± 513.0 | 5.6 | |
+/+ | 4–6 m | 6; 147 | 126.8 ± 28.0 | 24.8 ± 6.2 | 2802.3 ± 972.2 | 5.1 |
−/− | 5; 119 | 107.6 ± 19.9 | 32.5 ± 7.0 | 2834.1 ± 721.9 | 3.3 | |
I685T/I685T | 4; 125 | 115.7 ± 24.2 | 28.9 ± 7.1 | 2846.2 ± 884.0 | 4.0 | |
+/− | 4; 170 | 131.3 ± 24.7 | 24.7 ± 5.7 | 2745.0 ± 824.7 | 5.3 | |
K489R/− | 4; 148 | 102.5 ± 22.4 | 33.5 ± 8.0 | 2827.0 ± 868.0 | 3.1 | |
I685T/− | 4; 142 | 112.8 ± 23.7 | 32.2 ± 8.4 | 2923.8 ± 961.7 | 3.5 |