Table 1.
Gut dysbiosis observed in human patients with MDD
| Gut dysbiosis | References | Etc. | |
|---|---|---|---|
| ↓ | Bacteroides | 15 | A-MDD |
| Dialister | |||
| Faecalibacterium | |||
| Prevotella | |||
| ↑ | Alistipes | ||
| Blautia | |||
| Clostridium XIX | |||
| Lachnospiracea incertae sedis | |||
| Megamonas | |||
| Parabacteroides | |||
| Parasutterella | |||
| Phascolarctobacterium | |||
| Oscillibacter | |||
| ↓ | Escherichia/Shigella | R-MDD | |
| Oscillibacter | |||
| Dialister | |||
| Faecalibacterium | |||
| Prevotella | |||
| Ruminococcus | |||
| ↑ | Alistipes | ||
| Bacteroides | |||
| Parabacteroides | |||
| Phascolarctobacterium | |||
| Roseburia | |||
| ↓ | Howardella | 17 | MDD-F |
| Sutterella | |||
| Pyramidobacter | |||
| ↑ | Actinomyces | ||
| Bifidobacterium | |||
| Asaccharobacter | |||
| Atopobium | |||
| Eggerthella | |||
| Gordonibacter | |||
| Olsenella | |||
| Eubacterium | |||
| Anaerostipes | |||
| Blautia | |||
| Roseburia | |||
| Faecalibacterium | |||
| Desulfovibrio | |||
| ↓ | Anaerovorax | MDD-M | |
| Gordonibacter | |||
| Pyramidobacter | |||
| ↑ | Bacteroides | ||
| Erysipelotrichaceae incertae sedis | |||
| Veillonella | |||
| Atopobium | |||
| ↑ | phylum Firmicutes | 20 | |
| ↓ | phylum Bacteriodetes | ||
| ↑ | Prevotella | ||
| Klebsiella | |||
| Streptococcus | |||
| Clostridium XI | |||
a↓, decreased compared to control; ↑, increased compared to control.
bA-MDD, active-major depressive disorder; R-MDD, responded-major depressive disorder; MDD-F, female patients with MDD; MDD-M, male patients with MDD.
cDuplicate bacteria are indicated in bold.