Table 2. Dietary Niacin Intake and the Risk of New-Onset Hypertension Stratified by Quartiles and Combined Quartiles.
| Niacin intake, mg/d | Participants, No. | Events, No. (rate)a | Crude model | Adjusted modelb | ||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |||
| Quartiles | ||||||
| Q1 (<12.4) | 3061 | 1188 (51.7) | 1 [Reference] | 1 [Reference] | ||
| Q2 (12.4 to <14.3) | 3060 | 1166 (46.6) | 0.90 (0.83-0.97) | .009 | 0.95 (0.87-1.04) | .27 |
| Q3 (14.3 to <16.7) | 3061 | 952 (36.2) | 0.70 (0.64-0.76) | <.001 | 0.83 (0.75-0.90) | <.001 |
| Q4 (≥16.7) | 3061 | 998 (47.0) | 0.92 (0.85-1.00) | .05 | 1.08 (0.99-1.19) | .09 |
| Categories | ||||||
| Q1-2 (<14.3) | 6121 | 2354 (49.0) | 1.36 (1.26-1.47) | <.001 | 1.18 (1.09-1.28) | <.001 |
| Q3 (14.3 to <16.7) | 3061 | 952 (36.2) | 1 [Reference] | 1 [Reference] | ||
| Q4 (≥16.7) | 3061 | 998 (47.0) | 1.32 (1.21-1.44) | <.001 | 1.31 (1.20-1.44) | <.001 |
Abbreviations: HR, hazard ratio; Q, quartile.
SI conversion factor: To convert niacin to μmol/d, multiply by 8.123.
a
Incident rate is presented per 1000 person-years of follow-up.
b
Adjusted for age, sex, body mass index, smoking status, systolic blood pressure, diastolic blood pressure, region, education, and occupation, as well as energy intake and sodium to potassium intake ratio.