Table 1.

Key terms and definitions used in the ADAPT study

Adaptation	Intentional modification(s) of an evidence-informed intervention, in order to achieve better fit between an intervention and a new context.
Context	Any feature of the circumstances in which an intervention is implemented that may interact with the intervention to produce variation in outcomes.9 10
Core components	Those features in the intent and design of an intervention deemed responsible for the effectiveness of the intervention.2
Drift	A misapplication or a mistaken application of an intervention involving technical errors, abandonment of core components or introduction of counterproductive elements resulting in a loss of intervention benefits.11
Refinement	Modification(s) of an intervention to work in the same place or with the same population as originally designed and implemented.
Replication	The process of re-implementing an established intervention in a new context in a way that maintains fidelity to core goals, activities, delivery techniques, intensity and duration of the original study.12
Scale-out	The deliberate use of strategies to implement, test, improve and sustain an intervention as it is delivered to new populations and/or through new delivery systems that differ from those in effectiveness trials.13
Scale-up	The deliberate effort to broaden the delivery of an evidence-based intervention with the intention of reaching larger numbers of a target audience.13