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. 2021 Jan 6;156(4):334–342. doi: 10.1001/jamasurg.2020.6175

Table 2. Patient Characteristics Associated With Parathyroidectomy Among Medicare Beneficiaries With PHPT Based on Multivariable Logistic Regression.

Characteristic Unadjusted rate of parathyroidectomy, No./total No. (%) Adjusted OR (95% CI)
Sex
Female 13 684/44 569 (30.7) 1 [Reference]
Male 49 453/165 637 (29.9) 1.00 (0.98-1.03)
Age, y
66-75 42 024/117 960 (35.6) 1 [Reference]
76-85 19 010/73 491 (25.9) 0.68 (0.67-0.70)
≥86 2102/18 755 (11.2) 0.27 (0.26-0.29)
Race
White 56 888/183 433 (31.0) 1 [Reference]
Black 4741/19 797 (23.9) 0.67 (0.65-0.70)
Asian 390/1953 (20.0) 0.64 (0.57-0.72)
Hispanic 480/2280 (21.1) 0.66 (0.60-0.74)
American Native 150/453 (33.1) 0.97 (0.80-1.19)
Other 487/2290 (21.3) 0.62 (0.56-0.69)
ADI groupa
Advantaged
Most 12 717/52 899 (24.0) 1 [Reference]
Slightly 20 784/68 471 (30.4) 1.39 (1.35-1.43)
Disadvantaged
Slightly 22 093/65 887 (33.5) 1.61 (1.57-1.66)
Most 7542/22 949 (32.9) 1.66 (1.60-1.72)
Geography
Urban 51 689/178 718 (28.9) 1 [Reference]
Rural 11 447/31 488 (36.4) 1.18 (1.15-1.22)
Frailtyb
Robust 27 759/76 954 (36.1) 1 [Reference]
Prefrail 30 394/107 248 (28.3) 0.84 (0.82-0.86)
Mild 3531/18 316 (19.3) 0.61 (0.58-0.64)
Moderate to severe 1452/7688 (18.9) 0.60 (0.56-0.64)
Charlson Comorbidity Index score
0 19 069/51 534 (37.0) 1 [Reference]
1 15 372/47 758 (32.2) 0.88 (0.86-0.91)
≥2 28 695/110 914 (25.9) 0.77 (0.75-0.79)
Consensus guideline criteria
History
Nephrolithiasis 10 241/28 239 (36.3) 1.43 (1.39-1.47)
Osteoporosis 32 067/110 314 (29.1) 1.01 (0.99-1.03)
Stage 3 CKD 3565/17 566 (20.3) 0.71 (0.68-0.74)
Endocrinologist care 34 142/98 660 (34.6) 1.42 (1.40-1.45)

Abbreviations: ADI, Area Deprivation Index; CKD, chronic kidney disease; OR, odds ratio; PHPT, primary hyperparathyroidism.

a

Determined based on mailing zip code of beneficiary according to the Neighborhood Atlas.15

b

Determined based on the validated claims-based frailty index.18