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. 2021 Jan 6;157(2):1–9. doi: 10.1001/jamadermatol.2020.5213

Table 1. Dermoscopic Characteristics of Nonmelanocytic Lesions.

Diagnosis or feature Round 1: positive response, % Round 2: positive response, %
Basal cell carcinoma 96
Leaflike structures 96 100
Blue-gray ovoid nests 100 100
Multiple blue-gray dots and globules (buckshot scatter) 88 96
Spoke-wheellike structures/concentric structures 92 100
Ulceration/erosion 88 96
White shiny blotches and strands 85 89
Arborizing blood vessels 100 100
Short fine telangiectasias (superficial BCC)a 62 88
Rosette signb 42 12
Shiny white to red structureless and milky pink areas (glasslike translucency)a,b 27 12
Actinic keratosis 85
Rosette sign 77 89
Surface scale 73 85
Strawberry pattern (pink-red pseudonetwork +/– fine, wavy vessels [straight or coiled] surrounding hair follicles +/– white circles with central yellow clod [targetoid hair follicles])c 85 96
Pigmented actinic keratosis 85
Gray dots 81 89
Annular-granular pattern (gray dots around follicular openings) 71 92
Rosette sign 85 92
Surface scalea 89 100
Rhomboidal structuresb 62 35
White circles with central yellow clod (targetoid hair folliclesb 69 58
Gray-brown pseudonetworkb 58 27
Moth-eaten bordera,b 31 20
Patent folliclesa,b 38 40
Bowen disease (squamous cell carcinoma in situ) 89
Surface scale 81 100
Peripheral brown/gray dots arranged linearly (pigmented SCCIS) 77 92
Glomerular (coiled)/dotted blood vesselsd 96 100
Brown circles (pigmented SCCIS)b 54 27
Keratoacanthoma 85
Central keratin mass 92 100
Hairpin (looped) or serpentine (linear-irregular) blood vessels, usually at the periphery, with white-yellow haloe 96 100
Squamous cell carcinoma 96
Yellow keratin mass/scale-crust 85 100
Ulceration/blood spots/hemorrhagef 77 81
White circles (“keratin pearls”) 85 96
Rosette sign 81 92
Glomerular (coiled) blood vessels 88 100
Hairpin vessels, usually with whitish halo 92 96
Polymorphic blood vessel morphologya,b 42 28
Linear irregular (serpentine) blood vesselsa,b 42 32
Solar lentigo 96
Moth-eaten (sharply demarcated) borders 100 100
Homogenous light brown pigmentation 92 92
Networklike structures 77 85
Fingerprintlike structures (parallel lines)g 96 100
Simple lentigo (lentigo simplex) 85%
Symmetric with uniform pigment network 88 85
Seborrheic keratosis 96
Milialike cysts 100 100
Comedolike openings 100 100
Moth-eaten (sharply demarcated) borders 85 100
“Fissures and ridges”/gyri and sulci/cerebriform pattern 96 100
Fat-fingers 92 100
Fingerprintlike structures 85 96
Hairpin (looped) vessels, usually with whitish halo 96 100
Networklike structuresa 62 27
Lichen planuswlike keratosis/benign lichenoid keratosis 89%
Coarse gray granularity 92 96
Peppering (evenly spaced gray dots) 92 96
Sharp, cut off borders (scalloped/moth-eaten)a 73 84
Pinpoint/dotted blood vesselsa,b 31 16
Pigment network remnanta,b 46 32
Hemangioma/angioma 96%
Red, blue-red, or maroon lacunae/lagoons with white septae 100 100
Blue-black coloring (when thrombosed) 100 100
Angiokeratoma 96
Red/purple/black (“dark”) lacunae 100 100
Hemorrhagic crust 88 85
Whitish veila 62 54
Dermatofibroma 96
Central scarlike white patch with delicate surrounding networklike structures 100 100
Ringlike globules 81 89
Central shiny white lines (crystalline structures) 96 100
Vascular structures (vascular blush) within scarlike white patcha,b 50 52
Clear cell acanthoma 78
String of pearls (serpiginous) blood vessel pattern 100 100
Sebaceous hyperplasia 93%
Pale yellow lobules around a central follicular opening 100 100
Crown vessels 100 100
Poromaa,b 35

Abbreviations: BCC, basal cell carcinoma; SCCIS, squamous cell carcinoma in situ.

a

Objective did not reach consensus.

b

Objective suggested by a panelist.

c

Panelists voted to use this language instead of “strawberry pattern (pink-red pseudonetwork + fine, wavy vessels [straight or coiled] surrounding hair follicles + white circles with central yellow clod [targetoid hair follicles]).”

d

Panelists voted to use this language instead of “glomerular (coiled) blood vessels.”

e

Panelists voted to use this language instead of hairpin (looped) or serpentine (linear-irregular) blood vessels with white-yellow halo.”

f

Panelists voted to use this language instead of splitting into the 2 features “ulceration” and “blood spots/hemorrhage.”

g

Panelists voted equally between labeling this feature as “fingerprintlike structures” and “fingerprintlike structures (parallel lines). The latter was kept in order to be as inclusive as possible given equal outcomes in voting.