Table 4. Comparison of clinical and angiogenesis factors according to treatment type of rheumatoid arthritis patients (n=40).
| Mean±SD | Min-Max | Mean±SD | Min-Max | Mean±SD | Min-Max | P | |
|---|---|---|---|---|---|---|---|
| Duration of morning stiffness | 60.0±62.3 | 10-180 | 33.0±46.7 | 0-120 | 10.0±18.6 | 0-60 | 0.026 |
| Number of swollen joints | 8.7±5.1 | 1-15 | 2.9±3.2 | 0-10 | 3.9±3.7 | 0-10 | 0.038 |
| Number of sensitive joints | 14.5±7.9 | 1-21 | 10.8±8.3 | 1-27 | 13.1±8.9 | 0-26 | 0.529 |
| General assessment of patient condition | 5.8±1.2 | 4-7 | 3.6±1.8 | 1-7 | 4.3±2.1 | 1-7 | 0.041 |
| General assessment by the physician | 5.7±1.0 | 4-7 | 3.5±1.8 | 1-6 | 4.2±2.1 | 1-7 | 0.033 |
| Pain assessment of the patient | 5.7±1.2 | 4-7 | 3.7±1.9 | 1-7.5 | 4.5±1.9 | 1-7 | 0.072 |
| DAS28 score | 6.1±1.3 | 4.06-7.48 | 4.7±1.2 | 2.72-7.24 | 5.0±1.5 | 2.64-6.89 | 0.102 |
| Ritchie score | 17.0±7.1 | 5-26 | 10.2±5.2 | 3-23 | 10.9±5.5 | 2-17 | 0.067 |
| HAQ score | 0.9±0.5 | 0.25-1.62 | 0.6±0.57 | 0-2 | 0.6±0.4 | 0-1.37 | 0.429 |
| VEGF (pg/mL) | 387.3±319.7 | 162.52-926.21 | 586.9±354.5 | 120.39-1460 | 476.0±232.6 | 93.36-892.31 | 0.341 |
| ANG1 (pg/mL) | 55032.0±15531.2 | 40372.25-80179.12 | 66097.4±21212.0 | 24398.63-115656.58 | 55579.0±14354.4 | 36412.78-81210.54 | 0.119 |
| ANG2 (pg/mL) | 3696.3±1255.4 | 2453.56-5723.26 | 4384.5±1388.08 | 1584.82-7094.11 | 3630.9±1063.6 | 2169.10-5519.82 | 0.181 |
| Tie-2 (ng/mL) | 32.8±7.5 | 24.10-41.12 | 32.8±11.6 | 15.70-58.03 | 27.9±5.3 | 18-35.41G | 0.427 |
| SD: Standard deviation; Min: Minimum; Max: Maximum; DAS28: Disease activity score 28; HAQ: Health assessment questionnaire; VEGF: Vascular endothelial growth factor; ANG: Angiopoietin; Tie-2: Tyrosine-protein kinase receptor for angiopoietin; Kruskal-Wallis test was used. | |||||||