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. 2020 Jan 8;35(3):416–425. doi: 10.46497/ArchRheumatol.2020.7416

Table 4. Comparison of clinical and angiogenesis factors according to treatment type of rheumatoid arthritis patients (n=40).

  Mean±SD Min-Max Mean±SD Min-Max Mean±SD Min-Max P
Duration of morning stiffness 60.0±62.3 10-180 33.0±46.7 0-120 10.0±18.6 0-60 0.026
Number of swollen joints 8.7±5.1 1-15 2.9±3.2 0-10 3.9±3.7 0-10 0.038
Number of sensitive joints 14.5±7.9 1-21 10.8±8.3 1-27 13.1±8.9 0-26 0.529
General assessment of patient condition 5.8±1.2 4-7 3.6±1.8 1-7 4.3±2.1 1-7 0.041
General assessment by the physician 5.7±1.0 4-7 3.5±1.8 1-6 4.2±2.1 1-7 0.033
Pain assessment of the patient 5.7±1.2 4-7 3.7±1.9 1-7.5 4.5±1.9 1-7 0.072
DAS28 score 6.1±1.3 4.06-7.48 4.7±1.2 2.72-7.24 5.0±1.5 2.64-6.89 0.102
Ritchie score 17.0±7.1 5-26 10.2±5.2 3-23 10.9±5.5 2-17 0.067
HAQ score 0.9±0.5 0.25-1.62 0.6±0.57 0-2 0.6±0.4 0-1.37 0.429
VEGF (pg/mL) 387.3±319.7 162.52-926.21 586.9±354.5 120.39-1460 476.0±232.6 93.36-892.31 0.341
ANG1 (pg/mL) 55032.0±15531.2 40372.25-80179.12 66097.4±21212.0 24398.63-115656.58 55579.0±14354.4 36412.78-81210.54 0.119
ANG2 (pg/mL) 3696.3±1255.4 2453.56-5723.26 4384.5±1388.08 1584.82-7094.11 3630.9±1063.6 2169.10-5519.82 0.181
Tie-2 (ng/mL) 32.8±7.5 24.10-41.12 32.8±11.6 15.70-58.03 27.9±5.3 18-35.41G 0.427
SD: Standard deviation; Min: Minimum; Max: Maximum; DAS28: Disease activity score 28; HAQ: Health assessment questionnaire; VEGF: Vascular endothelial growth factor; ANG: Angiopoietin; Tie-2: Tyrosine-protein kinase receptor for angiopoietin; Kruskal-Wallis test was used.