Table 1. Clinical characteristics of patients with rheumatoid arthritis and healthy controls.
| RA patients (n=93) | Healthy controls (n=76) | p | |||||
| n | % | Mean±SD | n | % | Mean±SD | ||
| Age (year) | 53.3±11.3 | 50.3±13.9 | 0.119 | ||||
| Disease duration (month) | 90.5±66.7 | - | - | ||||
| DAS28 | 2.9±1.0 | - | - | ||||
| Sex | 0.213 | ||||||
| Female | 77 | 82.8 | 57 | 75.0 | |||
| Disease activity | |||||||
| Remission (DAS28 <2.6) | 46 | 49.5 | - | - | - | ||
| Low (DAS28 2.6-3.2) | 34 | 36.6 | - | - | - | ||
| Moderate (DAS28 3.2-5.1) | 8 | 8.6 | - | - | - | ||
| High (DAS28 >5.1) | 5 | 5.4 | - | - | - | ||
| Drugs | |||||||
| Corticosteroids Conventional (cDMARDs) |
57 | 61.3 | - | - | - | ||
| Methotrexate | 77 | 82.2 | |||||
| Hydroxychloroquine | 31 | 33.3 | |||||
| Sulfosalazine | 9 | 9.7 | |||||
| Leflunomide | 11 | 11.8 | |||||
| Biologic (bDMARDs) | 14 | 15.1 | |||||
| Lifestyle | |||||||
| Epilation* | 4 | 4.6 | 4 | 5.6 | 0.799 | ||
| Make-up* | 6 | 6.8 | 7 | 9.6 | 0.524 | ||
| Presence of pet* | 12 | 13.6 | 13 | 17.8 | 0.534 | ||
| Common towel use* | 40 | 45.5 | 42 | 57.6 | 0.174 | ||
| Use of a moisturizer* | 16 | 18.2 | 14 | 19.2 | 0.678 | ||
| Skin care* Skin type* |
1 | 1.13 | 4 | 5.6 | 0.118 | ||
| Oily | 21 | 23.9 | 13 | 17.6 | |||
| Dry | 37 | 42.0 | 34 | 46.6 | 0.617 | ||
| Combination The number of residents at home |
30 | 34.1 | 26 | 35.6 | |||
| 1-2 person | 34 | 36.6 | 21 | 27.6 | |||
| 3-4 person | 44 | 47.3 | 35 | 46.0 | 0.209 | ||
| >5 person Body washing | 15 | 16.1 | 20 | 26.3 | |||
| 1-2 times/week | 18 | 19.4 | 23 | 30.3 | |||
| 3-4 times/week | 38 | 40.9 | 32 | 42.1 | 0.145 | ||
| >5 times/week | 37 | 39.8 | 21 | 27.6 | |||
| Symptomst | |||||||
| Skin redness | 35 | 39.7 | 20 | 27.0 | 0.120 | ||
| Acne Itching | 17 | 19.3 | 19 | 25.7 | 0.352 | ||
| Eyes | 40 | 45.5 | 22 | 29.7 | 0.040 | ||
| Ears | 29 | 37.8 | 28 | 37.8 | 0.517 | ||
| Face | 20 | 22.7 | 17 | 22.9 | 0.998 | ||
| Demodex mite presence | 41 | 44.1 | 12 | 15.7 | <0.001 | ||
| Demodex folliculorum | 26 | 27.9 | 8 | 10.5 | 0.006 | ||
| Demodex brevis | 7 | 7.5 | 2 | 2.6 | 0.188 | ||
| Demodex species | 8 | 8.6 | 2 | 2.6 | 0.278 | ||
| Demodex infestation (> 5 Demodex/cm2) | 17 | 18.3 | 6 | 7.9 | 0.054 | ||
| Semiquantitative score | 0.807 | ||||||
| (<5 Demodex/cm2) (+) | 24 | 25.8 | 6 | 7.9 | |||
| (5-10 Demodex/cm2) (++) | 10 | 10.8 | 3 | 3.9 | |||
| (>10 Demodex/cm2) (+++) | 7 | 7.6 | 3 | 3.9 | |||
| RA: Rheumatoid arthritis; SD: Standard deviation; DAS28: Disease activity score 28; cDMARDs: Conventional disease-modifying anti- rheumatic drugs; bDMARDs: Biological disease-modifying anti-rheumatic drugs; * Eighty-eight rheumatoid arthritis patients and 73 healthy controls were included in the analysis; † Eighty-eight rheumatoid arthritis patients and 74 healthy controls were included in the analysis. | |||||||