Table 2. Comparison of rheumatoid arthritis patients with and without Demodex mite presence and Demodex infestation.
| Demodex mite presence (n=41) | Demodex infestation (n=17) | ||||||||
| n | n | % | Mean±SD | P | n | % | Mean±SD | p | |
| Age (year) | 0.780 | 0.535 | |||||||
| Positive | 41 | 53.7±12.1 | 17 | 51.8±12.3 | |||||
| Negative | 52 | 53.0±10.7 | 76 | 53.7±11.1 | |||||
| Disease duration (month) | 0.274 | 0.719 | |||||||
| Positive | 41 | 99.1±77.5 | 17 | 85.2±40.3 | |||||
| Negative | 52 | 83.7±57.2 | 76 | 91.6±71.7 | |||||
| Sex | 0.256 | 0.171 | |||||||
| Male | 16 | 5 | 31.3 | 1 | 6.3 | ||||
| Female | 77 | 36 | 46.8 | 16 | 20.8 | ||||
| Symptoms | |||||||||
| Skin redness | 35 | 16 | 44.4 | 0.476 | 7 | 20.0 | 0.740 | ||
| Acne Itching | 17 | 7 | 41.1 | 0.900 | 3 | 17.6 | 0.603 | ||
| Eyes | 40 | 14 | 35.0 | 0.222 | 7 | 17.5 | 0.918 | ||
| Ears | 29 | 9 | 31.0 | 0.142 | 4 | 13.8 | 0.569 | ||
| Face | 20 | 9 | 45.0 | 0.799 | 4 | 20.0 | 0.710 | ||
| Disease activity | 0.985 | 0.578 | |||||||
| Remission (DAS28 <2.6) | 46 | 20 | 43.5 | 9 | 19.6 | ||||
| Low (DAS28 2.6-3.2) | 34 | 15 | 44.1 | 7 | 20.6 | ||||
| Moderate (DAS28 3.2-5.1) | 8 | 4 | 50.0 | - | - | ||||
| High (>5.1) | 5 | 2 | 40.0 | 1 | 20.0 | ||||
| Non-corticosteroids | 36 | 18 | 50.0 | 0.361 | 7 | 19.4 | 0.817 | ||
| Corticosteroids | 57 | 23 | 40.4 | 10 | 17.5 | ||||
| One cDMARDs | 59 | 30 | 50.8 | 14 | 23.7 | ||||
| Two cDMARDs combination | 31 | 10 | 32.3 | 0.238 | 3 | 9.7 | 0.209 | ||
| Three cDMARDs combination | 2 | 1 | 50.0 | - | - | ||||
| Non-bDMARDs | 79 | 36 | 45.6 | 0.494 | 14 | 17.8 | 0.716 | ||
| bDMARDs | 14 | 5 | 35.7 | 3 | 21.4 | ||||
| SD: Standard deviation; DAS28: Disease activity score 28; cDMARDs: Conventional disease-modifying anti-rheumatic drugs; bDMARDs: Biological disease- modifying anti-rheumatic drugs. | |||||||||