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. 2020 Feb 7;35(3):376–384. doi: 10.46497/ArchRheumatol.2020.7699

Table 2. Comparison of rheumatoid arthritis patients with and without Demodex mite presence and Demodex infestation.

    Demodex mite presence (n=41)   Demodex infestation (n=17)  
  n n % Mean±SD P n % Mean±SD p
Age (year)         0.780       0.535
Positive 41     53.7±12.1   17   51.8±12.3  
Negative 52     53.0±10.7   76   53.7±11.1  
Disease duration (month)         0.274       0.719
Positive 41     99.1±77.5   17   85.2±40.3  
Negative 52     83.7±57.2   76   91.6±71.7  
Sex         0.256       0.171
Male 16 5 31.3     1   6.3  
Female 77 36 46.8     16   20.8  
Symptoms                  
Skin redness 35 16 44.4   0.476 7   20.0 0.740
Acne Itching 17 7 41.1   0.900 3   17.6 0.603
Eyes 40 14 35.0   0.222 7   17.5 0.918
Ears 29 9 31.0   0.142 4   13.8 0.569
Face 20 9 45.0   0.799 4   20.0 0.710
Disease activity         0.985       0.578
Remission (DAS28 <2.6) 46 20 43.5     9   19.6  
Low (DAS28 2.6-3.2) 34 15 44.1     7   20.6  
Moderate (DAS28 3.2-5.1) 8 4 50.0     -   -  
High (>5.1) 5 2 40.0     1   20.0  
Non-corticosteroids 36 18 50.0   0.361 7   19.4 0.817
Corticosteroids 57 23 40.4   10   17.5
One cDMARDs 59 30 50.8     14   23.7  
Two cDMARDs combination 31 10 32.3   0.238 3   9.7 0.209
Three cDMARDs combination 2 1 50.0     -   -  
Non-bDMARDs 79 36 45.6   0.494 14   17.8 0.716
bDMARDs 14 5 35.7   3   21.4
SD: Standard deviation; DAS28: Disease activity score 28; cDMARDs: Conventional disease-modifying anti-rheumatic drugs; bDMARDs: Biological disease- modifying anti-rheumatic drugs.