Table 6.

Isolation method characteristics

Manufacturer	Roche	ID-Solution	Taigen	Perkin Elmer
Robot	MagNA Pure 24 System	IDEAL	LabTurbo 24 AB	Chemagic 360D
	A	B	C	D
Product	MagNA Pure 24 Total NA Isolation Kit	IDXTRACT-MAG	Virus combo kit 24C-LVX480-1000	NextPrep-Mag cf DNA isolation kit
Type	Bead based	Bead based	Column	Bead based
Sample volume (mL)	2–4	0.5–5	0.3–3	0.5–10
Elution volume (µL)	30–200	30–120 (adaptable)	30–200	30–100
Level of automation	Full	Semi	Full	Semi
Manual pre processing		Reconstitute the PK and incubation (5 min at room temperature), addition of beads + buffers (incubation with vigorous shaking for 30 min at 56 °C). Adaptable distribution of buffers and elution reagents	Wash preparation: addition of EtOH	Add beads, add elution reagent in a bar or tube, reconstitute the Proteinase K
Hands-on-time (min)	0	45	5	20
Automated runtime (min)	90	45	70	70
Total runtime (min)	90	90	75	90
Samples	24	24	24	12
Cost of the instrument	+	+	+	++
Cost of consumables	++	+	++	+
Dimensions (cm)
Height × width × length	77.5 × 76.5 × 89.9	37 × 57 × 72	87 × 74 × 65	90 × 82 × 90