Table 1.
Grading system for radiation induced lung toxicity
| RTOG | CTCAE v. 5.0 | SWOG | |
|---|---|---|---|
| Grade 0 | No changes | No changes | Normal |
| Grade 1 | Asymptomatic or mild symptoms | Asymptomatic, only radiological, or tomographic findings | Radiographic changes, symptoms do not require steroids |
| Grade 2 | Moderate symptoms of pneumonitis (severe cough) and radiographic changes (radiographic patches) | Symptomatic, does not interfere with daily activities | Steroids required or tap of effusion |
| Grade 3 | Severe symptoms of pneumonitis, dense radiographic changes | Symptomatic, interferes with daily activities, requires supplemental O2 | Oxygen required |
| Grade 4 | Symptoms of severe respiratory failure requiring assisted ventilation or continuous O2 | Threatens life, requires mechanical ventilation support | Requires assisted ventilation |
| Grade 5 | Death-related late effects of radiotherapy | Death related severe pneumonitis | – |