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. 2021 Jan 6;21:13. doi: 10.1186/s12935-020-01707-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Further evaluation of PPP2R2B related immunity functions in TNBC. a, b The relationship between PPP2R2B expression and T cell immunity in TCGA and METABRIC, respectively. c–e The most related immune checkpoint family genes with PPP2R2B expression in TCGA. f–h The most related immune checkpoint family genes with PPP2R2B expression in METABRIC. GO:0002842 positive regulation of T cell mediated immune response to tumor cell; GO:0019882 antigen processing and presentation; GO:0042110 T cell activation; GO:0046631 alpha–beta T cell activation; GO:0046632 alpha–beta T cell differentiation; GO:2000553 positive regulation of T-helper 2 cell cytokine production; GO:2000556 positive regulation of T-helper 1 cell cytokine production. ns (Not significant), *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001