Table 2.
Relationship between RB1 gene deletion and disease stage, treatment status, β2 microglobulin level, 13q deletion rate and type
| RB1 gen deletion | Total | p value | ||
|---|---|---|---|---|
| Negative n (%) | Positive n (%) | |||
| RAI stage | ||||
| 0, 1, 2 | 25 (54) | 21 (46) | 46 | p > 0.05 |
| 3, 4 | 9 (64) | 5 (36) | 14 | |
| Total | 34 | 26 | 60 | |
| Treatment | ||||
| Positive | 15 (62) | 8 (35) | 23 | p > 0.05 |
| Negative | 24 (58) | 17 (42) | 41 | |
| Total | 39 | 25 | 64 | |
| β2 microglobuline | ||||
| < 3.5 mg/dl | 11 (61) | 7 (39) | 18 | p > 0.05 |
| > 3.5 mg/dl | 9 (60) | 6 (40) | 15 | |
| Total | 20 | 13 | 33 | |
| 13q deletion rate | ||||
| < 80% | 33 (63) | 19 (37) | 52 | p > 0.05 |
| > 80% | 8 (50) | 8 (50) | 16 | |
| Total | 41 (60) | 27 (40) | 68 | |
| < 70% | 23 (60,5) | 15 (39,5) | 38 | p > 0.05 |
| > 70% | 8 (42) | 11 (58) | 19 | |
| Total | 31 (54) | 26 (46) | 57 | |
| < 60% | 19 (59) | 13 (41) | 32 | p > 0.05 |
| > 60% | 12 (48) | 13 (52) | 25 | |
| Total | 31 (54) | 26 (46) | 57 | |
| Deletion type | ||||
| Monoallel | 37 (59) | 26 (41) | 63 | p > 0.05 |
| Biallel | 4 (80) | 1 (20) | 5 | |
| Total | 41 | 27 | 68 | |