Table 2.
Natural infection rates of Chrysops in the five study sites determined by microscopy and the loop-mediated isothermal amplification assay
| Study sites (years of MDA) | Microscopy method | Colorimetric LAMP assay | Fischer’s exact test (P-value) | ||
|---|---|---|---|---|---|
| Total number of wild-caught Chrysops flies screened | Number of positive flies (%) | Total number of wild-caught Chrysops of flies screened | Number of positive flies (%) | ||
| East MDA (9) | 2365 | 61 (3.3) | 183 | 30 (16.4) | 0.000 |
| East non-MDA (0) | 1861 | 103 (4.4) | 183 | 48 (26.2) | 0.000 |
| South-west 1 (15) | 2318 | 66 (2.8) | 434 | 137 (31.6) | 0.000 |
| South-west 2 (13) | 812 | 10 (1.2) | 200 | 1 (0.5) | 0.105 |
| North-west (10) | 485 | 17 (3.5) | 291 | 88 (30.2) | 0.000 |
| Total | 7841 | 257 (3.3) | 1291 | 304 (23.5) | 0.000 |
LAMP, Loop-mediated isothermal amplification; MDA , mass drug administration
East MDA, Messamena Health District; East non-MDA, Batouri Health District north-west (NWA Health District); South-west 1, Kumba Health District; South-west 2, Mamfe Health District. See section Study sites for a detailed description