Table 1.
Anthropometric characteristics, biochemical parameters and serum adipocytokines in obese and non-obese groups
| Variable | Obese (n = 62) | Non-obese (n = 32) | P |
|---|---|---|---|
| Age (yr)* | 39.55 ± 1.38 | 38.91 ± 2.63 | NS |
| Anthropometric characteristics* | |||
| Body weight (kg) | 115.8 ± 3.06 | 61.14 ± 2.01 | < 0.001 |
| BMI (kg/m2) | 45.76 ± 0.81 | 24.19 ± 0.70 | < 0.001 |
| Clinical parameter* | |||
| Fasting plasma glucose (mg/dL) | 107.1 ± 3.02 | 95.26 ± 2.81 | 0.006 |
| Fasting plasma insulin (μU/L) | 21.86 ± 2.36 | 10.73 ± 1.67 | < 0.001 |
| HOMA-IR | 5.38 ± 0.65 | 2.17 ± 0.24 | < 0.001 |
| HOMA-β | 242.4 ± 33.45 | 115.3 ± 18.56 | 0.001 |
| QUICKI | 0.31 ± 0.00 | 0.48 ± 0.12 | 0.035 |
| Serum adipocytokine† | |||
| CRP (μg/mL) | 52.56 ± 15.55 | 34.05 ± 19.09 | 0.006 |
| Adiponectin (μg/mL) | 39.88 ± 4.17 | 44.09 ± 7.33 | 0.593 |
| IL-8 (pg/mL) | 25.80 ± 38.45 | 36.39 ± 6.45 | 0.025 |
| MCP-1 (ng/mL) | 1.090 ± 0.17 | 0.75 ± 0.05 | 0.063 |
| Resistin (ng/mL) | 39.70 ± 5.98 | 36.53 ± 5.86 | 0.707 |
| IL-6 (pg/mL) | 26.88 ± 6.99 | 37.72 ± 32.72 | < 0.001 |
| TNF-α (pg/mL) | 38.20 ± 7.88 | 23.05 ± 3.63 | 0.084 |
Values are presented as mean± standard error of the mean.
The P-values obtained by using *Student t-test (unpaired) for parametric; †Mann-Whitney U-test for non-parametric variables between two groups (P<0.05 is considered significant).
NS, not significant; BMI, body mass index; HOMA-IR, homeostatic model assessment of insulin resistance; HOMA-β, homeostatic model assessment of β-cell function; QUICKI, quantitative insulin sensitivity check index; CRP, C-reactive protein; IL, interleukin; MCP, monocyte chemoattractant protein; TNF, tumor necrosis factor.