Table 2.
Anthropometric characteristics, biochemical parameters and serum adipocytokines in IR obese and IS obese subgroups
| Variable | IR obese (n = 43) | IS obese (n = 19) | P |
|---|---|---|---|
| Age (yr)* | 39.07 ± 1.66 | 40.63 ± 2.53 | NS |
| Anthropometric characteristics* | |||
| Body weight (kg) | 116.40 ± 3.92 | 114.30 ± 4.44 | 0.762 |
| BMI (kg/m2) | 46.20 ± 1.01 | 44.66 ± 1.34 | 0.399 |
| Clinical parameter* | |||
| Fasting serum glucose (mg/dL) | 107.40 ± 3.76 | 106.20 ± 5.02 | 0.862 |
| Fasting serum insulin (μU/L) | 25.74 ± 2.83 | 9.949 ± 1.76 | 0.003† |
| HOMA-IR | 6.53 ± 0.74 | 1.35 ± 0.15 | < 0.001 |
| HOMA-β | 284.40 ± 40.37 | 95.40 ± 21.72 | 0.017 |
| QUICKI | 0.30 ± 0.003 | 0.35 ± 0.01 | < 0.001 |
| HbA1c | 6.07 ± 0.09 | 5.83 ± 0.26 | 0.297 |
| Serum adipocytokines† | |||
| CRP (μg/mL) | 60.79 ± 20.04 | 33.90 ± 22.92 | 0.430 |
| Adiponectin (μg/mL) | 52.16 ± 6.61 | 72.17 ± 12.27 | 0.124 |
| IL-8 (pg/mL) | 152.40 ± 53.40 | 65.82 ± 31.69 | 0.179 |
| MCP-1 (ng/mL) | 1.05 ± 0.16 | 1.18 ± 0.43 | 0.177 |
| Resistin (ng/mL) | 38.37 ± 6.60 | 42.71 ± 12.8 | 0.741 |
| IL-6 (pg/mL) | 32.21 ± 9.70 | 14.82 ± 5.64 | 0.091 |
| TNF-α (pg/mL) | 35.45 ± 6.49 | 44.42 ± 21.46 | 0.510 |
Values are presented as mean± standard error of the mean.
The P-values obtained by using *Student t-test (unpaired) for parametric; †Mann-Whitney U-test for non-parametric variables between two groups (P<0.05 is considered significant).
IR, insulin-resistant; IS, insulin-sensitive; NS, not significant; BMI, body mass index; HOMA-IR, homeostatic model assessment of insulin resistance; HOMA-β, homeostatic model assessment of β-cell function; QUICKI, quantitative insulin sensitivity check index; HbA1c, glycosylated hemoglobin; CRP, C-reactive protein; IL, interleukin; MCP, monocyte chemoattractant protein; TNF, tumor necrosis factor.