Table 2.

USPSTF updated recommendation on screening for colorectal cancer.

USPSTF reviewed the evidence on the effectiveness of screening methodologies looking at their effect on reducing incidence and mortality. It also evaluated testing harms and performance characteristics, and commissioned a comparative modeling study to determine ideal starting and stopping ages, as well as screening intervals. Among the findings are the following:

There is high certainty that screening for colorectal cancer in average risk, asymptomatic adults aged 50–75 years are of substantial net benefit.

Multiple screening strategies are available, with different levels of evidence to support their effectiveness, as well as unique advantages and limitations.

There are no empirical data to demonstrate that any of the reviewed strategies provide a greater net benefit.

Screening for colorectal cancer is a substantially underused preventive health strategy in the United States.

USPSTF: US Preventive Services Task Force.