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. 2021 Jan 3;27:e929783-1–e929783-8. doi: 10.12659/MSM.929783

Table 1.

Comparisons of clinical characteristics between co-infected and mono-infected COVID-19 patients with univariate analysis.

Total Monoinfection group Coinfection group P value
Patients (n) 78 67 11
Sex 0.887
 Male 41 (52.6%) 35 (52.2%) 6 (54.5%)
 Female 37 (47.4%) 32 (47.8%) 5 (45.5%)
Age (years) 47.7±17.2 48.5±17.5 42.7±14.9 0.252
Age stratification (n) 0.832
 ≤20 5 (6.4%) 4 (6.0%) 1 (9.1%)
 21–40 24 (30.8%) 20 (29.9%) 4 (36.4%)
 41–60 28 (35.9%) 24 (35.8%) 4 (36.4%)
 >60 21 (26.9%) 19 (28.4%) 2 (18.2%)
Epidemiological history (positive, n) 66 (84.6%) 58 (86.6%) 8 (72.7%) 0.377
Symptom
 Fever 56 (71.8%) 47 (70.1%) 9 (81.8%) 0.425
 Cough 62 (79.5%) 53 (79.1%) 9 (81.8%) 0.836
 Expectoration 39 (50%) 34 (50.7%) 5 (45.5%) 0.745
 Fatigue 36 (46.2%) 28 (41.8%) 8 (72.7%) 0.056
 Shortness of breath 25 (32.1%) 23 (34.3%) 2 (18.2%) 0.288
 Chest tightness 7 (9.0%) 6 (9.0%) 1 (9.1%) 0.988
 Chest pain 3 (3.8%) 2 (3.0%) 1 (9.1%) 0.370
 Diarrhea 13 (16.7%) 12 (17.9%) 1 (9.1%) 0.467
 Muscular soreness 18 (23.1%) 16 (23.9%) 2 (18.2%) 0.678
Physical examination
 Body temperature (°C) 37.3 (36.7–38.5) 37.4 (36.7–38.5) 37.3 (36.8–39.1) 0.714
 Blood oxygen saturation level (%) 98.0 (96.0–98.0) 98.0 (96.0–98.0) 98.0 (95.5–98.0) 0.749
 Pulse rate (beats/min) 88.2±10.8 87.6±11.1 92.0±8.3 0.588
 Respiratory rate (breaths/min) 20 (20–20) 20 (20–20) 20 (20–25) 0.921
CT scan result 78 (100.0%) 67 (100.0%) 11 (100.0%) 0.467
 Ground-glass opacity (GGO) 65 (83.3%) 55 (82.1%) 10 (90.9%)
 No obvious abnormalities 13 (16.7%) 12 (17.9%) 1 (9.1%)
Chronic disease
 Diabetes 8 (10.3%) 7 (10.4%) 1 (9.1%) 0.891
 Cardiovascular and cerebrovascular diseases 19 (24.4%) 17 (25.4%) 2 (18.2%) 0.607
 Chronic obstructive pulmonary disease (COPD) 6 (7.7%) 6 (9.0%) 0 (0.0%) 0.586
 Chronic liver disease 6 (7.7%) 5 (7.5%) 1 (9.1%) 1.000
Clinical severity classification 0.555
 Mildly group 8 (10.3%) 6 (9.0%) 2 (18.2%)
 Moderately group 59 (75.6%) 52 (77.6%) 7 (63.6%)
 Severely/critically group 11 (14.1%) 9 (13.4%) 2 (18.2%)
Onset time (days) 4.0 (2.0–6.0) 4.0 (2.8–7.0) 3.0 (1.5–4.0) 0.173
length of stay (days) 13 (11–20) 14 (10–21) 13 (12–14) 0.205

Quantitative variables are expressed as median (interquartile range) or mean±standard deviation; categorical variables are expressed as frequencies (percentages);CT – computerized tomography.