Table 1.
Variable
|
All (n = 190)
|
AILDs (n = 114)
|
NAFLD (n = 66)
|
Age, yr | 46.36 ± 12.82 | 48.72 ± 11.57 | 42.15 ± 13.80 |
Male sex, n (%) | 45 (23.68) | 23 (20.18) | 18 (27.27) |
BMI, kg/m2 | 23.97 ± 2.69 | 24.33 ± 1.80 | 23.63 ± 2.34 |
Prevalence of autoantibodies, n (%) | 134 (70.53) | 89 (78.07) | 37 (56.06) |
Laboratory | |||
AST, U/L | 63.96 ± 86.42 | 72.54 ± 102.23 | 54.6 ± 59.10 |
ALT, U/L | 83.86 ± 86.42 | 81.98 ± 92.78 | 92.81 ± 78.67 |
LDH, U/L | 182.70 ± 35.43 | 183.02 ± 37.39 | 182.64 ± 32.86 |
AKP, U/L | 80.00 (63.00, 108.50) | 85.00 (62.25, 129.5) | 75.00 (64.00, 94.00) |
GGT, U/L | 103.67 ± 126.83 | 126.00 ± 151.92 | 76.82 ± 73.15 |
Total bilirubin, mg/dL | 10.90 (8.10, 15.30) | 11.20 (8.30, 16.70) | 9.80 (6.95, 14.15) |
Direct bilirubin, mg/dL | 3.60 (2.80, 4.90) | 3.70 (2.90, 5.70) | 3.45 (2.52, 4.50) |
Histological steatosis stage, n (%) | |||
S0 (< 5%) | 22 (11.6) | 20 (11.1) | 0 (0.0) |
S1 (5%-33%) | 85 (44.7) | 61 (33.9) | 16 (24.2) |
S2 (> 33%-66%) | 55 (28.9) | 28 (15.6) | 27 (40.9) |
S3 (> 66%) | 28 (14.7) | 5 (2.8) | 23 (34.8) |
Histological fibrosis stage, n (%) | |||
F0 (no fibrosis) | 12 (6.3) | 1 (0.9) | 10 (15.2) |
F1 (portal fibrosis without septa) | 70 (36.8) | 38 (33.3) | 30 (45.5) |
F2 (portal and periportal fibrosis with few septa) | 64 (33.7) | 40 (35.1) | 18 (27.3) |
F3 (portal and periportal fibrosis with numerous septa without cirrhosis) | 35 (18.4) | 26 (22.8) | 8 (12.1) |
F4 (cirrhosis) | 9 (4.7) | 9 (7.9) | 0 (0.0) |
CAP, dB/m | 270.17 ± 54.52 | 261.73 ± 53.80 | 290.97 ± 50.68 |
LSM, kPa | 7.66 ± 5.57 | 8.48 ± 6.50 | 6.61 ± 3.66 |
Distributions are expressed as the mean ± SD or median (interquartile range) or number (percentage). AIH: Autoimmune hepatitis; NAFLD: Nonalcoholic fatty liver disease; BMI: Body mass index; AKP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CAP: Controlled attenuation parameter; GGT: Gamma-glutamyl transferase; LDH: Lactate dehydrogenase; LSM: Liver stiffness measurement.