Extended Data Fig. 4. Circulating leukocytes and bone marrow progenitors in tumor bearing mice following MI or sham surgery.
(a) Numbers of circulating leukocytes and relative proportion of neutrophils, eosinophils, lymphocytes and basophils in E0771 tumor bearing mice after MI (n=8) or sham (n=8) surgery. (b,c) Flow cytometric analysis of bone marrow hematopoietic and stem cell populations in E0771 tumor bearing mice 9 days post-MI or sham surgery (12 days post-tumor cell implantation). LSK: Lineage–Sca1–cKit+ cells; CMP: common myeloid progenitor; GMP: granulocytic myeloid progenitor; MEP: megakaryocyte–erythroid progenitor. (a-c) two independent experiments were conducted. Data are the mean ± s.e.m. P values were calculated using a two-way analysis of variance (ANOVA), with results not significant (p>0.05) (a), or a two-tailed unpaired Student’s t-test (c).