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. 2020 Dec 26;12(12):1529–1552. doi: 10.4252/wjsc.v12.i12.1529

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Summary of the various soluble factors secreted by mesenchymal stem cells and their functions. HGF: Hepatocyte growth factor; TGF-β: Transforming growth factor–β; IDO: Indoleamine 2,3-dioxygenase; PGE2: Prostaglandin E2; IL: Interleukin; DCs: Dendritic cells; CCL: CC-chemokine ligand; NKs: Natural killer cells; MSCs: Mesenchymal stem cells; CXCR: C-X-C chemokine receptor type; VEGF: Vascular endothelial growth factor; IGF: Insulin-like growth factor; FGF: Fibroblast growth factor; Nrf2: Nuclear factor erythroid-related factor 2; HIF: Hypoxia-inducible factor; SDF: Stromal cell-derived factor; PDGF: Platelet-derived growth factor; ANG1: Angiogenesis 1; MCP-1: Monocyte chemotactic protein-1; ROS: Reactive oxygen species; hCAP: Human cathelicidin anti-microbial peptide; HO-1: Heme oxygenase; NO: Nitric oxide.