Table 3.
Logistic regression analysis for in-hospital mortality
| Characteristic | Univariate logistic regression | Multivariate logistic regression (model 1) | Multivariate logistic regression (model 2) | |||
|---|---|---|---|---|---|---|
| OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | |
| Age | 1.55 (1.011–1.101) | 0.014 | ||||
| Preoperative | ||||||
| APACHE II score | 1.194 (1.051–1.356) | 0.006 | ||||
| CKD (eGFR < 60 ml/min) | 1.233 (0.582–2.614) | 0.584 | ||||
| EuroSCORE II | 1.435 (1.103–1.867) | 0.007 | ||||
| Intraoperative | ||||||
| Operative time | 1.570 (1.208 – 2.041) | 0.001 | ||||
| CPB time | 1.007 (1.001–1.013) | 0.018 | ||||
| Amount of blood transfusion | 1.078 (1.021 – 1.139) | 0.007 | 1.078 (1.000–1.162) | 0.049 | ||
| Postoperative | ||||||
| MAP | 0.962 (0.927–0.998) | 0.038 | ||||
| The total amount of blood transfusion | 1.077 (1.050–1.103) | < 0.001 | ||||
| Mechanical ventilation time | 2.734 (1.903–3.928) | < 0.001 | ||||
| SOFA score | 1.538 (1.283–1.845) | < 0.001 | ||||
| Hb | 0.976 (0.957–0.995) | 0.015 | ||||
| PLT | 0.985 (0.977–0.993) | < 0.001 | ||||
| AKI | 7.539 (1.709–33.251) | 0.008 | ||||
| Advanced AKI | 29.732 (11.507–76.821) | < 0.001 | 19.408 (6.553–57.482) | < 0.001 | 16.560 (5.154–53.212) | < 0.001 |
| Use of CRRT | 18.939 (6.485 – 55.313) | 0.001 | ||||
| Use of PE/BA | 15.846 (1.848 – 135.879) | 0.012 | ||||
| Use of ECMO | 22.270 (2.693–184.155) | 0.004 | ||||
| Peak TB concentration | 1.018 (1.001–1.025) | < 0.001 | ||||
| Peak direct bilirubin concentration | 1.024 (1.015–1.033) | < 0.001 | ||||
| Peak indirect bilirubin concentration | 1.013 (1.001–1.026) | 0.035 | ||||
| Time to peak TB concentration | 1.808 (1.458–2.242) | < 0.001 | 1.557 (1.259–1.926) | < 0.001 | ||
| Time to peak TB concentration ≥ 5 days | 25.850 (10.218–65.399) | < 0.001 | 22.384 (6.767–74.035) | < 0.001 | ||
| ICU stay time | 1.285 (1.152–1.433) | < 0.001 | ||||
ACC, aortic cross clamp; AKI, acute kidney injury; APACHEII, acute physiology and chronic health evaluation II; BA, bilirubin adsorption; CPB, cardiopulmonary bypass; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; ICU, intensive care unit; MAP, mean arterial pressure; PE, plasma exchange; PLT, platelet; SOFA, sequential organ failure assessment; TB, total bilirubin