Table 1.
A summary of literature review of MCN with amyloid casts
| Journals | Case No | Hematology | κ:λ | Mean age (range) | Sex (F:M) | Amyloid casts (%) | Amyloid deposit in other kidney compartments | Systemic amyloid | Acute kidney injury (n) | Dialysis at diagnosis | Duration of follow up (months) | Endpoint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Virchows Arch A 1980 | Autopsy N = 4 | MM (n = 4) | 3:1 | 71 (59–82) | 3:1 | ND | None | 2/4 pancreas | ND | NA | NA | NA |
| Kidney Int 2007 | Biopsy N = 1 | MM (n = 1) | 0:1 | 52 | 0:1 | ND | Vessels and glomeruli | marrow and synovia | 1 | 1 | NA | ESRD, alive |
| Kidney Int 2008 | Biopsy N = 1 | MM (n = 1) | 0:1 | 60 | 0:1 | ND | None | ND | 1 | 1 | NA | ESRD, alive |
| Am J Kidney Dis 2009 | Biopsy N = 1 | MM (n = 1) | 0:1 | 59 | 1:0 | ND | None | ND | 1 | 1 | NA | ESRD, alive |
| Intern Med 2015 | Biopsy N = 1 | MM (n = 1) | 0:1 | 74 | 0:1 | ND | None | ND | 0 | 1 | 15 | ESRD, alive |
| Mod Pathol 2018 | Biopsy N = 17 | MM (n = 16) | 4:13 | 67 (47–87) | 7:10 | < 5%: n = 9 5% ~ 25%: n = 3 > 25%:n = 5 | 4 in tubular cells | 17/17 | 11 | 4 | 64 (Median) | Median OS: 21 months |
| Kidney Int 2019 | Biopsy N = 1 | MM (n = 1) | 0:1 | 53 | 1:0 | ND | None | None | 1 | 1 | 22 | ESRD, alive |
Abbreviations
NA not applicable
ND not determined
OS overall survival