Table 2.
Haematological reference intervals for healthy bare-nosed and southern hairy-nosed wombats obtained from the literature together with the mean, minimum and maximum values obtained from healthy bare-nosed wombats at all time points during the 25 mg/kg and 85 mg/kg trials
| Haematological parameter | Reference interval | 25 mg/kg trial (n = 5) | 85 mg/kg trial (n = 2) | |||
|---|---|---|---|---|---|---|
| BNW | SHNW | Mean | Min–max | Mean | Min–max | |
| Red blood cells (×1012/l) | 3.9–7.0 | 4.2–6.2 | 4.9 | 3.3–6.1 | 5.2 | 4.5–5.9 |
| Haemoglobin (g/l) | 77.6–168.6 | 108.8–163.6 | 123.2 | 80.0–153.0 | 124.2 | 113.0–136.0 |
| Haematocrit (l/l) | 0.3–0.5 | – | 0.4 | 0.2–0.5 | 0.4 | 0.3–0.4 |
| Mean corpuscular volume (fl) | 65.0–83.8 | 76.5–87.5 | 76a | 70.0–86.0 | 70.4a | 66.0–74.0 |
| Mean corpuscular haemoglobin (pg) | 12.7–32.3 | 24.1–28.9 | 25.4a | 24.0–28.0 | 24.0a | 22.0–26.0 |
| Mean cell haemoglobin concentration (g/l) | 288.7–377.1 | 299.3–343.9 | 333.8 | 303.0–357.0 | 340.9 | 321.0–358.0 |
| White blood cells (× 109/l) | 0.9–19.7 | 0–18.7 | 9.1 | 4.7–15.3 | 8.6 | 6.3–11.2 |
| Neutrophils (× 109/l) | 0.8–10.5 | 0–15.9 | 4.4 | 1.0–9.4 | 3.6 | 2.2–6.5 |
| Lymphocytes (× 109/l) | 0.0–14.7 | 0–3.4 | 3.9 | 1.5–8.7 | 4.3 | 1.8–7.7 |
| Monocytes (× 109/l) | 0.0–1.3 | 0–1.3 | 0.5 | 0.0–2.1 | 0.5 | 0.0–1.6 |
| Eosinophils (× 109/l) | 0.0–1.7 | 0–1.5 | 0.3 | 0.0–1.1 | 0.2 | 0.0–0.4 |
Parameters that deviated from reference intervals for bare-nosed or southern-hairy nosed wombats are highlighted in italics
aSignificant change observed over time-post fluralaner administration