Table 1.
The proportion of circRNAs with different functions in cancers
| The types of cancers | Acting as miRNA sponge | Regulating transcription | Binding to protein | Translating to protein | Other function |
|---|---|---|---|---|---|
| Hepatocellular carcinoma | 79.6% (39/49) | 2.0% (1/49) | 4.1% (2/49) | 2.0% (1/49) | 12.2% (6/49) |
| Lung cancer | 79.4% (27/34) | 2.9% (1/34) | / | / | 17.6% (6/34) |
| Breast cancer | 87.9% (29/33) | / | 3.0% (1/33) | / | 9.1% (3/33) |
| Gastric cancer | 84.8% (28/33) | 3.0% (1/33) | 6.1% (2/33) | / | 9.1% (3/33) |
| Glioma | 82.6% (19/23) | / | 4.3% (1/23) | 8.7% (2/23) | 4.3% (1/23) |
| Colorectal cancer | 69.6% (16/23) | 4.3% (1/23) | 8.7% (2/23) | / | 17.4% (4/23) |
| Bladder cancer | 94.7% (18/19) | / | / | / | 5.3% (1/19) |
| Osteosarcoma | 88.2% (15/17) | 5.9% (1/17) | 5.9% (1/17) | / | 5.9% (1/17) |
| Cervical cancer | 88.9% (8/9) | / | / | / | 11.1% (1/9) |
| Oral squamous cell carcinomas | 55.6% (5/9) | / | / | / | 44.4% (4/9) |
| Leukemia | 85.7% (6/7) | / | 14.3% (1/7) | / | / |
| Esophageal squamous cell carcinoma | 71.4% (5/7) | / | / | / | 28.6% (2/7) |
| Pancreatic cancer | 100.0% (6/6) | / | / | / | / |
| Pancreatic ductal adenocarcinoma | 100.0% (6/6) | / | / | / | / |
| Glioblastoma | 66.7% (4/6) | / | / | 16.7% (1/6) | 16.7% (1/6) |
| Prostate cancer | 75.0% (3/4) | / | / | / | 25.0% (1/4) |
| Nasopharyngeal carcinoma | 100.0% (3/3) | / | / | / | / |
| Renal carcinoma | 100.0% (3/3) | / | / | / | / |
| Papillary thyroid carcinoma | 100.0% (2/2) | / | / | / | / |
| Cutaneous squamous cell carcinoma | 100.0% (1/1) | / | / | / | / |