Table 3.
APOE genotypes counts and percentages derived from rs429358 and rs7412, by site and ancestry
| Site | ε2/ε2 | ε2/ε3 | ε2/ε4 | ε3/ε3 | ε3/ε4 | ε4/ε4 |
|---|---|---|---|---|---|---|
| CHOP | 0 | 5 (14) | 0 | 19 (54) | 10 (29) | 1 (2.9) |
| Cinc | 2 (0.7) | 41 (14) | 5 (1.7) | 146 (51) | 79 (28) | 14 (4.9) |
| Colu | 3 (0.5) | 73 (12) | 13 (2.1) | 373 (60) | 143 (23) | 13 (2.1) |
| Geis | 15 (1.2) | 171 (13) | 27 (2.1) | 769 (60) | 281 (22) | 15 (1.2) |
| Harv | 1 (0.1) | 120 (13) | 30 (3.2) | 561 (60) | 195 (21) | 25 (2.7) |
| Mayo | 14 (0.7) | 180 (9) | 41 (2) | 1170 (58) | 560 (28) | 58 (2.9) |
| Nwes | 8 (0.41) | 227 (12) | 51 (2.6) | 1189 (61) | 451 (23) | 36 (1.8) |
| UWKP | 10 (0.59) | 206 (12) | 22 (1.3) | 1059 (62) | 370 (22) | 18 (1.1) |
| Vand | 4 (2.7) | 18 (12) | 6 (4.1) | 77 (53) | 34 (23) | 7 (4.8) |
| Ancestry | ||||||
| AA | 3 (0.55) | 93 (17) | 24 (4.4) | 235 (43) | 167 (31) | 24 (4.4) |
| AS | 1 (0.15) | 87 (13) | 4 (0.61) | 444 (68) | 116 (18) | 3 (0.46) |
| EA | 49 (0.71) | 776 (11) | 152 (2.2) | 4157 (60) | 1658 (24) | 144 (2.1) |
| EA/AA | 4 (0.91) | 45 (10) | 14 (3.2) | 255 (58) | 105 (24) | 15 (3.4) |
| EA/AS | 0 | 39 (10) | 1 (0.26) | 268 (70) | 75 (19.5) | 1 (0.26) |
| UN | 0 | 1 (14) | 0 | 4 (57) | 2 (29) | 0 |
| Total | 57 (0.64) | 1041 (12) | 195 (2.1) | 5363 (60) | 2123 (24) | 187 (2.1) |
Chop Children’s hospital of Philadelphia, Cinc Cincinnati, Colu Columbia, Geis Geisinger, Harv Harvard, Mayo Mayo Clinic, news Northwestern, UWKP University of Washington and Kaiser Permanente Washington, Vand Vanderbilt, AA African American, AS Asian American, EA European American, UN unknown