Table 3.

Role category breakdown of protein coding genes in Ehrlichia species

Role Category1	EHF	ECH	EMU	EmCRT	Unique in EHF2
Amino acid biosynthesis	22	23	23	22
Biosynthesis of cofactors, prosthetic groups, and carriers	64	60	65	61
Cell envelope	53	51	51	48	1
Cellular processes	42	41	42	41
Central intermediary metabolism	3	3	5	3
DNA metabolism	41	44	41	42
Energy metabolism	84	82	80	83
Fatty acid and phospholipid metabolism	20	19	21	21
Mobile elements	4	4	4	4
Protein fate	79	78	77	78
Protein synthesis	108	108	107	107
Nucleotide biosynthesis	35	35	35	35
Regulatory functions	14	15	13	14
Transcription	21	21	19	19
Transport and binding proteins	33	33	32	33
Hypothetical proteins or proteins with unknown functions	244	276	268	255	8
Total Assigned Functions:	623	617	615	611
Total Proteins	867	893	883	866

¹Abbreviations: EHF Ehrlichia sp. HF, ECH E. chaffeensis Arkansas, EMU E. muris subsp. muris AS145, EmCRT E. muris subsp. eauclairensis Wisconsin.

²Proteins specific to Ehrlichia sp. HF are based on 4-way comparison analysis among four Ehrlichia spp. by Blastp (E < 1e-10)