Table 3.

15 hub genes identified by five algorithms of cytoHubba

Gene symbol	Description	log2FC	Q value	Regulation
CXCL13	C–X–C motif chemokine ligand 13	2.846	0.012	Up
CD52	CD52 molecule	1.928	0.004	Up
GZMA	Qranzyme A	1.753	0.022	Up
CD27	CD27 molecule	1.419	0.004	Up
CEP55	Centrosomal protein 55	1.264	0.01	Up
SKA3	Spindle and kinetochore associated complex subunit 3	1.215	3.03E−07	Up
IL21R	Interleukin 21 receptor	1.208	7E−04	Up
DLGAP5	DLG associated protein 5	1.172	0.027	Up
PRC1	Protein regulator of cytokinesis 1	1.112	0.042	Up
EOMES	eomesodermi	1.108	0.031	Up
TTK	TTK protein kinas	1.065	0.006	Up
CDCA8	Cell division cycle associated 8	1.049	1.74E−08	Up
UHRF1	Ubiquitin-like with PHD and ring finger domains 1	1.048	0.016	Up
KIAA0101	PCNA clamp associated factor	1.017	0.013	Up
FNBP1L	Formin binding protein 1 like	−1.325	0.004	Down

Annotation: FC: fold change, Q value: adjust P-value. The gene symbol in bold indicates eight hematologic/immune system-specific expressed hub genes