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. 2021 Jan 6;21:12. doi: 10.1186/s12935-020-01710-0

Table 3.

XPF expression in CRC, adenoma and anal benign disease tissue

Category Group Cases (−) (+) (++) (+++) PR (%) P
n (%) n (%) n (%) n (%)
Overall CRC 276 131 116 17 12 52.5% <0.001
Adenoma 202 116 67 15 4 42.6%
Anal disease 62 55 6 1 0 11.3%
Male CRC 143 66 62 9 6 53.8% <0.001
Adenoma 24 19 4 0 1 20.8%
Anal disease 19 17 1 1 0 10.5%
Female CRC 105 58 39 6 2 44.8% 0.001
Adenoma 26 16 6 2 2 38.5%
Anal disease 42 37 5 0 0 11.9%
≤60 CRC 119 62 47 7 3 47.9% 0.001
Adenoma 26 18 6 1 1 30.8%
Anal disease 38 32 5 1 0 15.8%
>60 CRC 129 62 54 8 5 51.9% <0.001
Adenoma 24 17 4 1 2 29.2%
Anal disease 22 21 1 0 0 4.5%
Colon CRC 82 54 21 3 4 34.1% 0.275
Adenoma 10 8 2 0 0 20.0%
Rectum CRC 166 70 80 12 4 57.8% 0.109
Adenoma 33 22 6 2 3 33.3%

PR positive rate. Negative (−), light positive (+), positive (++), strong positive (+++) staining. Mann–Whitney U- test of nonparametric test to compare the XPF protein expression between CRC and adjacent tissue

The italics values: P < 0.05