Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 6;22:11. doi: 10.1186/s12859-020-03940-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — Annotation tool comparison using CPR bacteria genomes. Given the smaller genome sizes and lower completeness levels, all tools required shorter times to perform annotations (a). While the standard mode of MicrobeAnnotator only takes ~ 2 h to annotate a genome, the light version takes only a couple of minutes like other tools that use smaller databases. Consequently, the RAM usage for these smaller genomes decreases but is still on par with DRAM requirements (b). As expected for genomes with lower representation in the databases, all tools could annotate a lower percentage of proteins. However, MicrobeAnnotator was able to find more matches for hypothetical proteins, having one of the lowest percentages of unannotated proteins of all tools (c). MA MicrobeAnnotator, MAL MicrobeAnnotator Light, EGG EggNOG-Mapper, IPS InterProScan, PROK Prokka. A: Annotated, H: Hypothetical, U: Unannotated