Table 1.
Recommended ASCVD risk enhancing factors for individuals with borderline and intermediate-risk
| Family history of premature CVD |
| Persistently elevated LDL-C ≥ 160 mg/dl |
| Chronic kidney disease |
| Metabolic syndrome |
| Condition-specific to women (e.g. HDP, premature menopause, GDM/macrosomia) |
| Inflammatory disease (especially rheumatoid arthritis, psoriasis, HIV) |
| Ethnicity (e.g. south Asian ancestry) |
| Lipid biomarkers |
| Persistently elevated triglycerides ≥ 175 mg/dl |
| In selected individuals, if measured |
| hs-CRP ≥ 2 mg/dl |
| LP (a) levels ≥ 50 mg/dl |
| apoB ≥ 130 mg/dl |
| Ankle-brachial index (ABI) < 0.9 |
CVD cardiovascular disease, LDL-C low-density lipoprotein cholesterol, hs-CRP highly sensitive C-reactive protein; LP (a) lipoprotein (a), GDM gestational diabetes, HDP hypertensive disorders pregnancy