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. 2021 Jan 6;19:25. doi: 10.1186/s12967-020-02686-1

Table 1.

Recommended ASCVD risk enhancing factors for individuals with borderline and intermediate-risk

Family history of premature CVD
Persistently elevated LDL-C ≥ 160 mg/dl
Chronic kidney disease
Metabolic syndrome
Condition-specific to women (e.g. HDP, premature menopause, GDM/macrosomia)
Inflammatory disease (especially rheumatoid arthritis, psoriasis, HIV)
Ethnicity (e.g. south Asian ancestry)
Lipid biomarkers
 Persistently elevated triglycerides ≥ 175 mg/dl
In selected individuals, if measured
 hs-CRP ≥ 2 mg/dl
 LP (a) levels ≥ 50 mg/dl
 apoB ≥ 130 mg/dl
 Ankle-brachial index (ABI) < 0.9

CVD cardiovascular disease, LDL-C low-density lipoprotein cholesterol, hs-CRP highly sensitive C-reactive protein; LP (a) lipoprotein (a), GDM gestational diabetes, HDP hypertensive disorders pregnancy