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. 2021 Jan 6;18:10. doi: 10.1186/s12974-020-02054-2

Fig. 9.

Fig. 9

Spinal NET+ nerve fiber detection in APP/PS1 and WT mice. a The NET+ nerve fibers in the lumbar spinal cord were detected by immunofluorescence. b The NET+ area in the two groups of mice decreased significantly with aging. The expression of NET in 12-month-old APP/PS1 mice was significantly lower than those of WT mice of the same age and 3-month-old APP/PS1 mice. n = 6. ns, not significant. ***P < 0.001, #P < 0.05 compared with other time points in the same group. ▲P < 0.001 compared with 12 m WT mice