Table 7. Association of LEPR haplotypes with PCOS in Bahraini and Tunisian subjects.
Bahraini | Tunisian | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Haplotype | Total | Cases | Controls | χ2 | P | Total | Cases | Controls | χ2 | P |
T A A | 0546 | 0.529 | 0.564 | 1.057 | 0.304 | 0.526 | 0.529 | 0.524 | 0.035 | 0.852 |
T A G | 0.174 | 0.229 | 0.115 | 19.559 | 9.75 × 10−6 | 0.266 | 0.279 | 0.258 | 0.745 | 0.388 |
C G G | 0.096 | 0.101 | 0.091 | 0.244 | 0.621 | 0.087 | 0.087 | 0.086 | 0.007 | 0.935 |
C A A | 0.079 | 0.070 | 0.090 | 1.165 | 0.281 | 0.053 | 0.047 | 0.057 | 0.727 | 0.394 |
T G A | 0.041 | 0.015 | 0.068 | 15.733 | 7.29 × 10−5 | 0.008 | 0.006 | 0.010 | 0.650 | 0.420 |
C A G | 0.026 | 0.028 | 0.023 | 0.298 | 0.585 | 0.023 | 0.023 | 0.023 | 0.012 | 0.912 |
T G G | 0.023 | 0.021 | 0.026 | 0.192 | 0.662 | 0.037 | 0.029 | 0.042 | 1.539 | 0.215 |
C G A | 0.015 | 0.007 | 0.024 | 4.297 | 0.038 |
LEP three-locus haplotype (rs2025804, rs1137100, rs1137101); boldface and underlined indicate minor allele.