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. 2021 Jan 6;41(1):BSR20200869. doi: 10.1042/BSR20200869

Figure 3. Centrality analysis and module analysis of the PPI network acquired through cytoNCA and MCODE plugins of Cytoscape.

Figure 3

(A) A density diagram of degree centrality. (B) A density diagram of betweenness centrality. (C) A density diagram of closeness centrality. (D) The intersection of the top 30% molecules in each centrality (degree, betweenness, closeness) was detected by Venny2.1. Results showed 147 key DEGs were chosen for further study because of their high degree, betweenness and closeness. (E) The most significant module was obtained from the PPI network which contained 34 nodes and 49 edges.