TABLE 1.
Demographic, Clinical, and Laboratory Characteristics Based on Cirrhosis Status
| Trait | Overall | No Cirrhosis | Cirrhosis | P Value |
|---|---|---|---|---|
| N = 1,382 | n = 470 | n = 770 | ||
| Age (n = 1,030) | 67.0 ± 10.9 | 67.0 ± 11.7 | 66.9 ± 10.5 | 0.97 |
| % male | 68.4% | 71.3% | 65.70% | 0.045 |
| Ethnicity | ||||
| Asian | 46.2% | 61.1% | 44.3% | <0.001 |
| Living in Asia | 42.1% | 56.4% | 40.0% | <0.001 |
| Living in United States | 4.1% | 4.7% | 4.3% | 0.78 |
| Caucasian | 33.9% | 28.5% | 35.1% | 0.018 |
| Hispanic | 7.0% | 4.2% | 10.1% | <0.001 |
| African American | 0.8% | 0.9% | 0.7% | 0.74 |
| Other | 3.0% | 2.8% | 3.4% | 0.62 |
| Screening (n = 313) | 25.0% | 15.8% | 30.2% | 0.012 |
| Mean Child‐Pugh‐Turcotte score | N/A | N/A | 7.0 (6.0, 8.0) | N/A |
| Comorbidities | ||||
| Diabetes mellitus (n = 948) | 60.7% | 49.0% | 68.3% | <0.001 |
| Hypertension (n = 899) | 60.4% | 58.4% | 61.3% | 0.35 |
| Dyslipidemia (n = 403) | 44.9% | 55.0% | 41.0% | 0.009 |
| Coronary artery disease (n = 830) | 24.2% | 27.1% | 22.2% | 0.096 |
| Chronic obstructive pulmonary disease (n = 620) | 2.7% | 4.0% | 2.2% | 0.16 |
| Chronic kidney disease (n = 488) | 10.6% | 12.5% | 9.5% | 0.26 |
| Myocardial infarction (n = 210) | 10.7% | 11.2% | 10.5% | 0.83 |
| Congestive heart failure (n = 211) | 9.4% | 10.0% | 9.2% | 0.82 |
| Cerebrovascular disease (n = 208) | 9.1% | 5.7% | 11.2% | 0.17 |
| Obesity (n = 720) | 54.0% | 56.7% | 51.3% | 0.17 |
| Laboratory values | ||||
| White blood cell count (K/µL) (n = 773) | 6.1 (4.6, 8.1) | 6.9 (5.5, 8.6) | 5.5 (4.1, 7.3) | <0.001 |
| Hemoglobin (g/dL) (n = 752) | 12.8 (11.1, 14.0) | 13.2 (11.6, 14.4) | 12.4 (10.7, 13.8) | <0.001 |
| Platelet count (K/µL) (n = 778) | 160.5 (109.0, 227.8) | 207.5 (154.0, 268.0) | 121.0 (82.5, 187.0) | <0.001 |
| Creatinine (mg/dL) (n = 750) | 0.9 (0.8, 1.2) | 0.9 (0.8, 1.2) | 1.0 (0.8, 1.2) | 0.59 |
| Sodium (mEq/L) (n = 371) | 139.0 (136.0, 141.0) | 139.0 (136.0, 140.5) | 139.0 (136.0, 141.0) | 0.84 |
| International normalized ratio (n = 731) | 1.1 (1.0, 1.2) | 1.0 (1.0, 1.1) | 1.1 (1.0, 1.3) | <0.001 |
| Aspartate aminotransferase (U/L) (n = 747) | 50.0 (35.0, 82.0) | 44.0 (31.0, 81.0) | 54.0 (39.0, 82.0) | <0.001 |
| Alanine aminotransferase (U/L) (n = 832) | 39.0 (26.0, 60.0) | 39.0 (26.0, 63.0) | 39.0 (27.0, 58.8) | 0.71 |
| Total bilirubin (mg/dL) (n = 853) | 0.9 (0.6, 1.5) | 0.7 (0.5, 1.0) | 1.1 (0.7, 2.0) | <0.001 |
| Alkaline phosphatase (U/L) (n = 650) | 123.5 (85.0, 207.2) | 110.0 (74.0, 190.0) | 130.5 (90.0, 211.0) | 0.002 |
| ALBI index (n = 678) | 2.0 (1.0, 2.0) | 2.0 (1.0, 2.0) | 2.0 (2.0, 2.0) | <0.001 |
| MELD‐sodium score (n = 681) | 9.2 (7.5, 12.3) | 7.6 (6.5, 10.0) | 10.2 (8.2, 13.7) | <0.001 |
Data are depicted as mean ± SD, median (interquartile range), or percentages.