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. 2020 Sep 14;319(5):F796–F808. doi: 10.1152/ajprenal.00187.2020

Fig. 3.

Fig. 3.

Effects of RAR-related orphan receptor C (Rorc) mutation on renal ischemia-reperfusion (I/R) injury and lymphocyte expression. A: Lewis Rorc+/+ vs. Rorc−/− rats were subjected to 40 min of bilateral renal I/R injury and allowed to recover for 2 days. Serum creatinine values 24 h following recovery are shown. Results from two experimental cohorts were combined and pooled with values from individual animals shown. BF: tissues from one cohort were analyzed for inflammatory cells. Shown are total mononuclear cells (B), total CD4+ cells (C), total CD8+ cells (D), total IL-17+ (E), and T helper (Th)17 cells (F) expressed as means ± SE positive cells per gram of kidney. *P < 0.05 vs. sham-operated control; †P < 0.05 Rorc+/+ vs. Rorc−/− rats, by one-way ANOVA and the Student–Newman–Keuls post hoc test.