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. 2020 Oct 5;319(5):F848–F862. doi: 10.1152/ajprenal.00383.2020

Table 2.

Proteins with substantial changes in abundance in response to PKA-Cβ deletion [Pmod < 0.02 and |log(ratio)| > 0.5]

UniProt ID Gene Symbol Annotation Log2 (PKA-Cα Null/ PKA-Cα Intact) Pmod Value Log2 (PKA-Cβ Null/ PKA-Cβ Intact) Pmod Value
Q8VCT4 Ces1d Carboxylesterase 1D −0.370 0.440 −1.358 0.013
Q8CEZ4 Mab21l4 Protein mab-21-like 4 0.180 0.652 −1.351 0.005
P30115 Gsta3 Glutathione S-transferase A3 −0.294 0.202 −1.334 6.23 × 10−5
P08074 Cbr2 Carbonyl reductase [NADPH] 2 −0.178 0.683 −1.186 0.017
Q8JZM8 Muc4 Mucin-4 −0.396 0.353 −1.144 0.017
P00329 Adh1 Alcohol dehydrogenase 1 0.334 0.348 −1.094 0.008
Q7TPW1 Nexn Nexilin 0.228 0.349 −0.881 0.003
Q9D939 Sult1c2 Sulfotransferase 1C2 −0.535 0.065 −0.869 0.007
Q62469 Itga2 Integrin α2 −0.074 0.743 −0.696 0.009
Q99LB7 Sardh Sarcosine dehydrogenase, mitochondrial −0.163 0.457 −0.591 0.017
Q9WUU7 Ctsz Cathepsin Z −0.053 0.786 −0.562 0.013
Q8R3G9 Tspan8 Tetraspanin-8 −0.199 0.212 −0.557 0.003
P22935 Crabp2 Cellular retinoic acid-binding protein 2 −0.282 0.088 −0.534 0.004
P63082 Atp6v0c V-type H+-ATPase 16-kDa proteolipid subunit −0.101 0.556 −0.526 0.009
Q80V42 Cpm Carboxypeptidase M −0.077 0.607 −0.516 0.004
P12265 Gusb β-Glucuronidase −0.032 0.819 −0.516 0.003
P17563 Selenbp1 Methanethiol oxidase −0.122 0.525 −0.506 0.019
Q5FWI3 Cemip2 Cell surface hyaluronidase 0.020 0.899 0.508 0.008
P55264 Adk Adenosine kinase −0.297 0.059 0.513 0.004
Q99PT3 Ino80b INO80 complex subunit B 0.048 0.658 0.551 2.66 × 10−4
Q8K0C4 Cyp51a1 Lanosterol 14-α demethylase −0.313 0.117 0.563 0.011
P28661 Septin4 Septin-4 0.235 0.106 0.690 2.90 × 10−4
Q80Z25 Ofd1 Oral-facial-digital syndrome 1 protein homolog 0.518 0.020 0.826 0.001
P26645 Marcks Myristoylated alanine-rich C-kinase substrate 1.486 0.003 1.718 0.001
P68181 Prkacb cAMP-dependent protein kinase catalytic subunit β 0.717 0.038

Pmod value, moderated P value.