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. 2020 Oct 5;319(5):F848–F862. doi: 10.1152/ajprenal.00383.2020

Table 4.

Phosphopeptides changed most convincingly in PKA-Cβ -null cells versus PKA-Cβ intact [Pmod < 0.01 and |log(ratio)| > 0.5]

UniProt ID Gene Symbol Amino Acid Number Annotation Sequence Log2 (PKA-Cα Null/ PKA-Cα Intact) Pmod Value Log2 (PKA-Cβ Null/ PKA-Cβ Intact) Pmod Value
Q6NZF1 Zc3h11a 740 Zinc finger CCCH domain-containing protein 11A RLS*SASTGKPPLSVEDDFEK −0.71 0.006 −1.00 0.001
Q67FY2 Bcl9l 118 B cell CLL/lymphoma 9-like protein SVS*VDSGEQR −0.75 0.002 −0.86 0.001
Q03173 Enah 719 Protein enabled homolog APST*STPEPTR 0.00 0.988 −0.79 0.002
Q9QZQ1 Mllt4 1201 Afadin ITSVS*TGNLCTEEQSPPPRPEAYPIPTQTYTR −0.05 0.793 −0.77 0.002
O08796 Eef2k 66 Eukaryotic elongation factor 2 kinase T*ECGSTGSPASSFHFK −0.13 0.552 −0.75 0.004
Q03173 Enah 720 Protein enabled homolog APSTS*TPEPTR −0.11 0.633 −0.75 0.005
O55003 Bnip3 60 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 SSHCDS*PPR 0.27 0.222 −0.70 0.007
Q2VPU4 Mlxip 9 MLX-interacting protein AADVFM^CS*PR −0.03 0.897 −0.68 0.010
Q8BUH8 Senp7 12 Sentrin-specific protease 7 RAS*SEIVTEGK −0.67 8.08 × 10−5 −0.67 8.49 × 10−5
P20357 Map2 1635 Microtubule-associated protein 2 S*GILVPSEK −0.65 0.005 −0.66 0.004
Q8VDZ4 Zdhhc5 409 Palmitoyltransferase ZDHHC5 SEPSLEPESFRS*PTFGK −0.27 0.144 −0.64 0.003
Q8CGF1 Arhgap29 1241 Rho GTPase-activating protein 29 ESSEEPALPEGT*PTCQRPR −0.04 0.743 −0.63 0.001
Q8VI36 Pxn 258 Paxillin IS*ASSATR −0.01 0.966 −0.62 0.004
Q8C6B2 Rtkn 518 Rhotekin T*FSLDAAPADHSLGPSR −0.01 0.962 −0.60 0.005
Q8C6B2 Rtkn 520 Rhotekin TFS*LDAAPADHSLGPSR −0.13 0.423 −0.60 0.002
A1A535 Veph1 422 Ventricular zone-expressed PH domain-containing protein 1 INAESNT*PGSGR −0.34 0.070 −0.59 0.005
Q9Z2H5 Epb41l1 540 Band 4.1-like protein 1 RLPS*SPASPSPK −0.17 0.332 −0.57 0.006
P28661 Sept4 68 Septin-4 PQS*PDLCDDDVEFR −0.02 0.917 −0.55 0.003
Q8C5R2 Proser2 223 Proline and serine-rich protein 2 LAGNEALSPTS*PSK −0.26 0.119 −0.55 0.004
Q99MR1 Gigyf1 227 GRB10-interacting GYF protein 1 ST*SPDGGPR −0.05 0.640 −0.51 0.001
Q99MR1 Gigyf1 226 GRB10-interacting GYF protein 1 S*TSPDGGPR 0.05 0.723 −0.50 0.003
Q60864 Stip1 481 Stress-induced-phosphoprotein 1 HDS*PEDVK −0.12 0.498 0.57 0.005

PKA-Cα-null data for the same peptides are also given for comparison. Pmod value, moderated P value. *Phosphorylated amino acids.