Table 8.

AKAPs and cAMP-associated proteins with altered phosphorylation in either PKA-Cα or PKA-Cβ-null cells

UniProt ID	Gene Symbol	Annotation	Amino Acid Number	Centralized Sequence†	Log2(PKA-Cα Null/ PKA-Cα Intact)	Pmod Value	Log2(PKA-Cβ Null/ PKA-Cβ Intact)	Pmod Value
O08715	Akap1	A-kinase anchor protein 1, mitochondrial	101	TRQVRRRS*ESSGNLP	−0.41	0.003	0.00	0.966
Q9WTQ5	Akap12	A-kinase anchor protein 12	22	PAESDTPS*ELELSGH	0.55	0.035	−0.09	0.716
Q9WTQ5	Akap12	A-kinase anchor protein 12	583	AEAEEGAT*SDGEKKR	0.43	0.018	0.11	0.490
Q9WTQ5	Akap12	A-kinase anchor protein 12	584	EAEEGATS*DGEKKRE	0.64	0.008	−0.02	0.908
Q9WTQ5	Akap12	A-kinase anchor protein 12	683	KRARKASS*SDDEGGP	0.51	0.011	−0.11	0.514
Q9WTQ5	Akap12	A-kinase anchor protein 12	684	RARKASSS*DDEGGPR	0.52	0.019	−0.20	0.305
Q9WTQ5	Akap12	A-kinase anchor protein 12	1292	SNEEQSIS*PEKREMG	0.40	0.061	0.49	0.026
Q3UEI1	Pde4c	cAMP-specific 3′,5′-cyclic phosphodiesterase 4C	301	ELRRSSHT*SLPTAAI	−0.43	0.034	0.26	0.173
P70453	Pde7a	High-affinity cAMP-specific 3′,5′-cyclic phosphodiesterase 7A	58	FETERRGS*HPYIDFR	−0.44	0.020	−0.40	0.031
Q5EG47	Prkaa1	5′-AMP-activated protein kinase catalytic subunit α1	496	ATPQRSGS*ISNYRSC	−0.41	0.009	−0.13	0.347
Q9DBC7	Prkar1a	cAMP-dependent protein kinase type I-α regulatory subunit	83	DSREDEIS*PPPPNPV	−1.01	3.99 × 10−4	0.05	0.816
P31324	Prkar2b	cAMP-dependent protein kinase type II-β regulatory subunit	112	NRFTRRAS*VCAEAYN	−1.38	0.001	−0.29	0.402

P_mod value, moderated P value.

^*Phosphorylated amino acids. R or K in positions −3 and −2 are underlined.