Table 2.
Covariate balance in the final matched dataset: Surgery (plus adjuvant therapies) versus primary endocrine therapy (PET).
| Surgery |
PET |
||
|---|---|---|---|
| N = 422 | N = 238 | ||
| Age | n | 422 | 238 |
| Mean (SD) | 80.57 (5.36) | 81.30 (5.94) | |
| Median (IQR) | 81.00 (76.00, 84.00) | 82.00 (77.00, 85.75) | |
| Min, Max | 70, 94 | 70, 96 | |
| aPG-SGA | Low | 343 (81.3%) | 190 (79.8%) |
| Moderate | 62 (14.7%) | 39 (16.4%) | |
| High | 17 (4.0%) | 9 (3.8%) | |
| ADL | No dependency | 271 (64.2%) | 134 (56.3%) |
| Mild dependency | 54 (12.8%) | 34 (14.3%) | |
| Moderate/severe dependency | 97 (23.0%) | 70 (29.4%) | |
| iADL | No dependency | 250 (59.2%) | 124 (52.1%) |
| Mild dependency | 73 (17.3%) | 38 (16.0%) | |
| Moderate/severe dependency | 99 (23.5%) | 76 (31.9%) | |
| MMSE | Normal function | 351 (83.2%) | 191 (80.3%) |
| Mild impairment | 60 (14.2%) | 39 (16.4%) | |
| Moderate impairment | 8 (1.9%) | 6 (2.5%) | |
| Severe | 3 (0.7%) | 2 (0.8%) | |
| CCI | 0 | 312 (73.9%) | 161 (67.6%) |
| 2 | 110 (26.1%) | 77 (32.4%) | |
| ECOG-PS | Low | 370 (87.7%) | 194 (81.5%) |
| Moderate | 36 (8.5%) | 27 (11.3%) | |
| High | 16 (3.8%) | 17 (7.1%) | |
| Medications | 3 or fewer | 176 (41.7%) | 100 (42.0%) |
| 4 or more | 246 (58.3%) | 138 (58.0%) | |
| NPI | Moderate | 217 (51.4%) | 125 (52.5%) |
| Good | 194 (46.0%) | 107 (45.0%) | |
| Poor | 11 (2.6%) | 6 (2.5%) | |
Abbreviations. aPG-SGA: abridged patient generated subjective global assessment. ADL: activities of global living. IADL: instrumental activities of global living. MMSE: mini mental state examination. CCI: Charlson comorbidities index. ECOG-PS: Eastern cooperative oncology group performance status. NPI: Nottingham prognostic index. SD: Standard deviation. IQR: interquartile range.