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. 2021 Jan 7;19:29. doi: 10.1186/s12967-020-02692-3

Table 2.

Radiological characteristics of patients with COVID-19 and non-COVID-19 pneumonia in the training, validation, and testing cohorts

Characteristics Training cohort (n = 379) P value Validation cohort (n = 131) P value Testing cohort (n = 40) P value
Non-COVID-19 group (n = 313) COVID-19 group (n = 66) Non-COVID-19 group (n = 102) COVID-19 group (n = 29) Non-COVID-19 group (n = 20) COVID-19 group (n = 20)
Number (%) < 0.001 0.001 0.025
 Single 179 (57.2) 5 (7.6) 64 (62.7) 8 (27.6) 12 (60.0) 5 (25.0)
 Multiple 134 (42.8) 61 (92.4) 38 (37.3) 21 (72.4) 8 (40.0) 15 (75.0)
Location (%) 0.131  > 0.999 0.339
 Unilateral lung 33 (10.5) 3 (4.5) 6 (5.9) 2 (6.9) 4 (20.0) 1 (5.0)
 Bilateral lungs 280 (89.5) 63 (95.5) 96 (94.1) 27 (93.1) 16 (80.0) 19 (95.0)
Distribution (%)  < 0.001  < 0.001 0.006
 Peripheral 48 (15.3) 46 (69.7) 19 (18.6) 15 (51.7) 6 (30.0) 16 (80.0)
 Central 24 (7.7) 1 (1.5) 3 (2.9) 1 (3.4) 1 (5.0) 0 (0.0)
 Peripheral and Central 241 (77.0) 19 (28.8) 80 (78.4) 13 (44.8) 13 (65.0) 4 (20.0)
Density (%) 0.544 0.469 0.067
 Pure GGO 76 (24.3) 13 (19.7) 20 (19.6) 8 (27.6) 11 (55.0) 4 (20.0)
Pure consolidation 75 (24.0) 14 (21.2) 23 (22.5) 4 (13.8) 3 (15.0) 4 (20.0)
 GGO with consolidation 162 (51.8) 39 (59.1) 59 (57.8) 17 (58.6) 6 (30.0) 12 (60.0)
Accompanying features (%)
 Reticulation 22 (7.0) 27 (40.9)  < 0.001 13 (12.7) 8 (27.6) 0.102 9 (45.0) 7 (35.0) 0.519
 Air bronchogram 168 (53.7) 34 (51.5) 0.749 52 (51.0) 15 (51.7) 0.944 6 (30.0) 9 (45.0) 0.327
Other findings (%)
 Pleural effusion 31 (9.9) 10 (15.2) 0.212 12 (11.8) 2 (6.9) 0.683 1 (5.0) 0 (0.0)  > 0.999
 Lymphadenopathy 46 (14.7) 1 (1.5) 0.003 11 (10.8) 2 (6.9) 0.790 2 (10.0) 0 (0.0) 0.468
CT score, median (IQR) 4.0 (3.0) 5.0 (3.0)  < 0.001 3.0 (3.0) 5.0 (4.5) 0.042 2.5 (3.5) 4.5 (4.8) 0.157

IQR inter-quartile range