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Kaplan–Meier survival curves in vaccinees and controls as assessed by qPCR. Kaplan–Meier curves in subjects undergoing controlled human malaria infection (CHMI) after the last of three doses with 2.7 × 106 PfSPZ (n = 16) or 1.0 × 105 PfSPZ Challenge (n = 13) vs. pooled saline (n = 5) and oral chloroquine plus saline controls (n = 2). The median time from the last dose to CHMI was 14 weeks for PfSPZ Vaccine and 15 weeks for PfSPZ-CVac. This figure appears in color at www.ajtmh.org.
