Table 4.
Vascular predictors of intracranial (MCA) pulsatility in adults 18–85 yr of age (n = 262)
| Model 1 |
Model 2 |
Model 3 |
||||
|---|---|---|---|---|---|---|
| B (95%CI) | β | B (95%CI) | β | B (95%CI) | β | |
| Age2 | 0.00 (0.00,0.00) | 0.45 (0.33,0.57)** | 0.00 (0.00,0.00) | 0.44 (0.28,0.59)** | 0.00 (0.00,0.00) | 0.38 (0.25,0.52)** |
| BMI | −0.00 (−0.01,0.00) | −0.05 (−0.16,0.06) | −0.00 (−0.01,0.00) | −0.06 (−0.16,0.06) | −0.00 (−0.01,0.00) | −0.07 (−0.17,0.03) |
| Female sex | 0.02 (−0.01,0.05) | 0.09 | 0.02 (−0.01,0.05) | 0.07 | 0.03 (0.01,0.06) | 0.13* |
| Ao:CCA PWV | 0.05 (0.01,0.09) | 0.15 (0.04,0.26)** | 0.06 (0.03,0.10) | 0.18 (0.08,0.27)** | ||
| CCA diameter | −0.01 (−0.03,0.02) | −0.03 (−0.15,0.10) | −0.02 (−0.05,0.01) | −0.09 (−0.19,0.02) | ||
| CCA IMT | −0.02 (−0.16,0.11) | −0.03 (−0.18,0.13) | −0.03 (−0.15,0.08) | −0.04 (−0.17,0.10) | ||
| CCA PP | 0.00 (0.00,0.01) | 0.26 (0.15,0.38)** | ||||
| CCA W1 | 0.01 (0.01,0.02) | 0.25 (0.14,0.36)** | ||||
| Adjusted R2 | 0.25 | 0.26 | 0.44 | |||
| ΔR2 | 0.25 | 0.01 | 0.18 | |||
| F statistic | 18.19 | 12.45 | 21.44 | |||
Model adjusted for antihypertensive and statin medication use. BMI, body mass index; Ao:CCA PWV, ratio of aortic to carotid pulse wave velocity; CCA, common carotid artery; IMT, intima-media thickness; PP, pulse pressure; β 95% confidence interval (CI) not calculated for noncontinuous variables. Bold highlights significant effect, P < 0.05.
*
P < 0.05;
**
P < 0.01.