Table 2. Differently expressed genes in C. difficile cultivated in absence and presence of L-lactate.
gene name | Log2 fold change exp | adj. p-value exp | Log2 fold change stat | adj. p-value stat | Annotation (according to [28]) | |
---|---|---|---|---|---|---|
CDIF630erm_01318 | larA | 1.52 | 5.94E-05 | 1.42 | 6.16E-07 | lactate racemase |
CDIF630erm_01319 | etfB4 | 1.21 | 2.60E-05 | 1.35 | 1.90E-06 | lactate dehydrogenase (electron bi-/ confurcating), electron transfer flavoprotein beta subunit |
CDIF360erm_01320 | etfA4 | 2.77 | 8.14E-07 | 2.88 | 9.05E-08 | lactate dehydrogenase (electron bi-/ confurcating), electron transfer flavoprotein alpha subunit |
CDIF630erm_01321 | 2.52 | 5.29E-07 | 2.59 | 8.83E-07 | lactate dehydrogenase (electron bi-/ confurcating), catalytic subunit |
The log2 fold changes of regulated genes (log2 fold change > 1, p-value < 0.01) measured by DNA array in the exponential and at the beginning of the stationary phase from cells cultivated in absence (CAM) and presence of 500 mg/L L-lactate (CAM+L) based on 4 independent cultivations are shown.