Table 3.
Performance on PABRQ between groupsa
| Beliefs Characteristicsb |
African American (n = 46) N (%) |
White (n = 60) N (%) |
Odds Ratios: White vs. African American | P values |
|---|---|---|---|---|
| Q1: Familiarity with informed consent processes? | 0.91 (0.18, 4.67) | 0.912 | ||
|
Not familiar (1,2) Generally familiar (3,4,5) |
24 (83) 5 (17) |
35 (85) 6 (15) |
||
| Q2: Familiarity with research subject protection measures? | 0.45 (0.14, 1.38) | 0.17 | ||
|
Not familiar (1,2) Generally familiar (3,4,5) |
9 (30) 21 (70) |
19 (45) 23 (55) |
||
| Q3: Were you ever asked to participate in research? | 0.53 (0.16, 1.68) | 0.289 | ||
|
No Yes |
10 (32) 21 (68) |
15 (37) 26 (63) |
||
| Q4: Have you ever participated in research? | 0.93 (0.31, 2.77) | 0.890 | ||
|
No Yes |
14 (47) 16 (53) |
18 (44) 23 (56) |
||
| Q5: Attitude towards research with human participants? | 0.46 (0.11, 1.72) | 0.251 | ||
|
Positive with reservations (3) Positive (4,5) |
23 (74) 8 (26) |
36 (86) 6 (14) |
||
| Q6: Attitude towards participating in research yourself? | 0.99 (0.07, 11.85) | 0.996 | ||
|
Negative Positive |
2 (6) 29 (94) |
2 (5) 39 (95) |
||
| Q7: Attitude towards someone in family/close friend participating in human research? | 0.84 (0.13, 5.17) | 0.855 | ||
|
Negative Positive |
3 (10) 28 (90) |
4 (10) 37 (90) |
||
| Q8: Attitude towards random assignment? | 0.69 (0.22, 2.12) | 0.518 | ||
|
Negative Positive |
9 (29) 22 (71) |
18 (44) 23 (56) |
||
| Q9: Opinion of participants being assigned to treatment vs. non-treatment? | 1.1 (0.37, 3.28) | 0.859 | ||
|
Negative Positive |
13 (42) 18 (58) |
18 (43) 24 (57) |
||
| Q10: Is it necessary to examine “new” drugs using science/ experiments before they are implemented? | 1.87 (0.57, 6.61) | 0.313 | ||
|
Never or sometimes (1,2,3) Always (4) |
22 (71) 9 (29) |
29 (69) 13 (31) |
||
| Q11: What motives do you think scientists have to conduct medical/clinical research (a-e): | ||||
| 11.a: The wish to find new treatments/examinations? | 0.82 (0.19, 3.32) | 0.776 | ||
|
Important (3) Very important (4) |
7 (23) 24 (77) |
6 (14) 36 (86) |
||
| 11.b: The wish to help patients? | 0.61 (0.17, 2.04) | 0.425 | ||
|
Slightly important (2,3) Very important (4) |
7 (23) 24 (77) |
11 (26) 31 (74) |
||
| 11.c: The wish to minimize total expenses in treatment/examination? | 0.62 (0.19, 1.93) | 0.408 | ||
|
Not very important (1,2,3) Very important (4) |
19 (61) 12 (39) |
30 (71) 12 (29) |
||
| 11.d: The wish to promote their own career? | 0.57 (0.19, 1.7) | 0.316 | ||
|
Not important (1,2) Important (3,4) |
15 (48) 16 (52) |
26 (62) 16 (38) |
||
| 11.e: The wish to increase knowledge generally? | 0.24 (0.06, 0.81) | 0.028* | ||
|
Not very important (2,3) Very important (4) |
7 (23) 24 (77) |
17 (40) 26 (60) |
||
Frequency of different characteristics may vary, and percentages may not be equal to 100% because of missing data
aLogistic regression controlling for age, sex, and education compared odds ratios of AA and White participants
bFor each question, there is a range of answers that participants can choose from. Answers have been categorically dichotomized
*P values, obtained by Wald’s test, indicate significant differences between AA and White groups at the 0.05 level