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. 2021 Jan 7;19:32. doi: 10.1186/s12967-020-02695-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — Interactions between SARS-CoV-2 proteins and differentially expressed genes of host. a Venn diagram showing the commonly deregulated genes between deregulated genes in our nasopharyngeal samples and Gordon et al. reported viral protein-interacting high confidence host proteins. Network representing the interactions between genes in b. Deregulated genes in nasopharyngeal samples along with SARS-CoV-2 proteins and Gordon et al. described viral interacting host proteins, and c Differentially expressed Integrin related genes in lungs compared to the nasal samples along with SARS-CoV-2 proteins and Gordon et al. described viral interacting host proteins. Hexagon, ellipse, rounded rectangle represents viral proteins, process-related genes, and proteins that interact with viral proteins, respectively. Expression values of the genes and represented in a color-coded scale. Color towards red indicating higher expression, while color towards green indicating little to no expression