. 2021 Jan 7;16(1):e0243788. doi: 10.1371/journal.pone.0243788

Table 1. CX3CR1 deficiency protects the heart from decompendation following TAC.

	A			B
	BL6 sham n = 8	BL6 TAC [21d] n = 7		CX3CR1^GFP/GFP sham n = 6	CX3CR1^GFP/GFP TAC [21d] n = 7
sBP carotis, mmHg	102 ± 20	167 ± 30	^***	115 ± 24	167 ± 24	^*
HR, beats/min	609 ± 25	594 ± 46	^ns	603 ± 20	639 ± 16	^ns
EF, %	39 ± 6	21 ± 10	^**	36 ± 8	48 ± 4	^ns; ^#^***
CO, μl/min	13370 ± 1694	6054 ± 2326	****	12724 ± 2983	11348 ± 1694	^ns; ^#^*
CI, μl/min/BW	548 ± 181	212 ± 87	****	459 ± 110	461 ± 62	^ns; ^#^*
ESV, μl	35 ± 5	46 ± 11	^ns	41 ± 7	21 ± 5	^^; ^#^*
EDV, μl	53 ± 5	51 ± 9	^ns	57 ± 8	34 ± 6	^*^; ^#^
dPdt_max, mm Hg/sek	15377 ± 3328	9508 ± 2654	^*	11024 ± 4783	12845 ± 2670	^ns

Part A indicating C57BL/6 data, Part B CX3CR1^GFP/GFP data; values are mean ± SD.

*p < 0.05.

**p < 0.01,

*** P<0.001; transverse aortic constriction (TAC) versus respective sham, ns = not significant versus respective sham.

^#p indicates TAC Wt vs. TAC CX3CR1^GFP/GFP; sBP carotis = systolic blood pressure in carotid artery; HR = heart rate; EF = ejection fraction; CO = cardiac output; CI = cardiac index; ESV = end-systolic volume; EDV = end-diastolic volume; dPdtmax is the maximal rate of rise of left ventricular pressure [21].